Isotretinoin

myotubularin related protein 11 ; Homo sapiens







51 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33658110 Does Systemic Isotretinoin Treatment Constitute a Predisposition to Allergic Sensitization? 2021 1
2 33919763 Pharmacokinetics and Safety of a Novel Oral Liquid Formulation of 13-cis Retinoic Acid in Children with Neuroblastoma: A Randomized Crossover Clinical Trial. 2021 Apr 14 1
3 34387230 Physeal Abnormalities in Children With High-risk Neuroblastoma Intensively Treated With/Without 13-Cis-Retinoic Acid. 2021 Oct 1 1
4 31562833 Isotretinoin is indirectly effective in sebocytes. 2020 Apr 1
5 31522242 Phase I trial of belinostat in combination with 13-cis-retinoic acid in advanced solid tumor malignancies: a California Cancer Consortium NCI/CTEP sponsored trial. 2019 Dec 1
6 28786105 Double-blind, randomized phase 3 trial of low-dose 13-cis retinoic acid in the prevention of second primaries in head and neck cancer: Long-term follow-up of a trial of the Eastern Cooperative Oncology Group-ACRIN Cancer Research Group (C0590). 2017 Dec 1 1
7 24858462 Interferon alpha plus 13-cis-retinoic acid modulation of BCL-2 plus paclitaxel for recurrent small-cell lung cancer (SCLC): an Eastern Cooperative Oncology Group study (E6501). 2014 Jul 1
8 25039756 Metabolic characteristics of 13-cis-retinoic acid (isotretinoin) and anti-tumour activity of the 13-cis-retinoic acid metabolite 4-oxo-13-cis-retinoic acid in neuroblastoma. 2014 Dec 3
9 22577058 Genetic variants in the PI3K/PTEN/AKT/mTOR pathway predict head and neck cancer patient second primary tumor/recurrence risk and response to retinoid chemoprevention. 2012 Jul 1 1
10 21235714 An enzymatic mechanism for generating the precursor of endogenous 13-cis retinoic acid in the brain. 2011 Apr 1
11 21292632 A strong case for personalized, targeted cancer prevention. 2011 Feb 1
12 21292633 Global assessment of genetic variation influencing response to retinoid chemoprevention in head and neck cancer patients. 2011 Feb 1
13 19646277 13-cis-retinoic acid re-differentiation therapy and recombinant human thyrotropin-aided radioiodine treatment of non-Functional metastatic thyroid cancer: a single-center, 53-patient phase 2 study. 2009 Aug 1 1
14 17987264 Retinoids induced astrocytic differentiation with down regulation of telomerase activity and enhanced sensitivity to taxol for apoptosis in human glioblastoma T98G and U87MG cells. 2008 Mar 1
15 18166465 Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts. 2008 Mar 15 1
16 18181979 Decreased plasma folate concentration in young and elderly healthy subjects after a short-term supplementation with isotretinoin. 2008 Jan 2
17 17163463 Induction of cell cycle arrest and apoptosis by a combined treatment with 13-cis-retinoic acid, interferon-alpha2a, and alpha-tocopherol in squamous cell carcinoma of the head and neck. 2007 Apr 1
18 16391896 Combination chemotherapy with 13-cis-retinoic acid and celecoxib in the treatment of glioblastoma multiforme. 2006 May 1
19 15806132 Pilot study of 13cis-retinoic acid+dexamethasone+alpha interferon as maintenance therapy following high-dose chemotherapy and autologous stem cell transplant for multiple myeloma. 2005 May 1
20 15961764 Randomized phase II/III trial of interferon Alfa-2a with and without 13-cis-retinoic acid in patients with progressive metastatic renal cell Carcinoma: the European Organisation for Research and Treatment of Cancer Genito-Urinary Tract Cancer Group (EORTC 30951). 2005 Jun 20 1
21 15138569 13-cis retinoic acid in head and neck cancer chemoprevention: results of a randomized trial from the Italian Head and Neck Chemoprevention Study Group. 2004 Jun 1
22 15263793 All-trans retinoic acid and interferon-alpha for treatment of human renal cell carcinoma multicellular tumor spheroids. 2004 1
23 12643008 A phase II study of 13-cis retinoic acid plus interferon alpha-2a in advanced stage penile carcinoma: an Eastern Cooperative Oncology Group study (E3893). 2003 1
24 12804041 Effects of 13-cis-retinoic acid on chemoimmunotherapy of metastatic renal cell carcinoma--results of a retrospective analysis. 2003 Apr 1
25 14581068 Novel inhibition of cis/trans retinoic acid interconversion in biological fluids--an accurate method for determination of trans and 13-cis retinoic acid in biological fluids. 2003 Nov 5 1
26 12168960 Transforming growth factor-alpha: a surrogate endpoint biomarker? 2002 Aug 1
27 12389622 Combination of 13-cis retinoic acid and interferon-alpha in the treatment of recurrent or refractory peripheral T-cell lymphoma. 2002 Jul 1
28 11408495 Combined interferon-alfa, 13-cis-retinoic acid, and alpha-tocopherol in locally advanced head and neck squamous cell carcinoma: novel bioadjuvant phase II trial. 2001 Jun 15 1
29 11505395 Phase II evaluation of paclitaxel, alpha-interferon, and cis-retinoic acid in advanced renal cell carcinoma. 2001 Aug 1 1
30 11509747 Embryonic subcellular distribution of 13-cis- and all-trans-retinoic acid indicates differential cytosolic/nuclear localization. 2001 Sep 2
31 10944130 Phase III trial of interferon alfa-2a with or without 13-cis-retinoic acid for patients with advanced renal cell carcinoma. 2000 Aug 1
32 11066455 Acute promyelocytic leukemia (AML-M3)--Part 1: Pathophysiology, clinical diagnosis, and differentiation therapy. 2000 Spring 1
33 10367173 Preliminary phase II clinical and pharmacokinetic study of 9-cis retinoic acid in advanced cervical cancer. New York Gynecologic Oncology Group. 1999 May-Jun 1
34 10378671 Phase II study of a combination of low-dose cisplatin with 13-cis-retinoic acid and interferon-alpha in patients with advanced head and neck squamous cell carcinoma. 1999 Apr 1
35 10550153 Placebo-controlled trial of 13-cis-retinoic acid activity on retinoic acid receptor-beta expression in a population at high risk: implications for chemoprevention of lung cancer. 1999 Nov 1
36 9806904 Recombinant human glutathione S-transferases catalyse enzymic isomerization of 13-cis-retinoic acid to all-trans-retinoic acid in vitro. 1998 Nov 15 2
37 9403338 Immunosuppressive activity of 13-cis-retinoic acid in rats: aspects of pharmacokinetics and pharmacodynamics. 1997 Oct 1
38 9589358 Effect of retinoic acid on HPV titration and colposcopic changes in Korean patients with dysplasia of the uterine cervix. 1997 1
39 7705672 Phase II study of 13-cis-retinoic acid plus interferon-alpha 2a in heavily pretreated squamous carcinoma of the cervix. 1995 Mar 1
40 7812199 Differentiation therapy of myelodysplastic syndromes with retinoic acid. 1994 Aug 1
41 8439447 13-cis-retinoic acid affects oxidation and DNA damage in oxidative-positive SLE lymphocytes but may not be useful for therapy. 1993 Feb 1
42 8457712 Phase II study of 13-cis-retinoic acid and interferon-alpha 2a in patients with advanced squamous cell lung cancer. 1993 Feb 1
43 1734084 13-cis-retinoic acid and interferon alpha-2a: effective combination therapy for advanced squamous cell carcinoma of the skin. 1992 Feb 19 1
44 1734085 13-cis-retinoic acid plus interferon alpha-2a: highly active systemic therapy for squamous cell carcinoma of the cervix. 1992 Feb 19 1
45 1918383 Immunosuppressive activity of 13-cis-retinoic acid and prevention of experimental autoimmune encephalomyelitis in rats. 1991 Oct 1
46 2252043 Treatment with 13-cis-retinoic acid in transfusion-dependent patients with myelodysplastic syndrome and decreased toxicity with addition of alpha-tocopherol. 1990 Dec 1
47 2522491 Enhancement of the expression of activation markers on human peripheral blood mononuclear cells by in vitro culture with retinoids and carotenoids. 1989 Mar 1
48 3278754 Randomized study of 13-cis retinoic acid v placebo in the myelodysplastic disorders. 1988 Mar 1
49 3320577 Combination of low-dose cytarabine and 13-cis retinoic acid in the treatment of myelodysplastic syndromes. 1987 1
50 6580071 Phase I clinical trial of 13-cis-retinoic acid in myelodysplastic syndromes. 1983 Nov 1