Title : Decreased plasma folate concentration in young and elderly healthy subjects after a short-term supplementation with isotretinoin.

Pub. Date : 2008 Jan

PMID : 18181979






2 Functional Relationships(s)
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1 BACKGROUND: In the last two decades, there has been an increasing use of isotretinoin (13-cis-retinoic acid or 13-CRA) for treatment of severe, and recently mild and moderate, acne in Westernized populations. Isotretinoin myotubularin related protein 11 Homo sapiens
2 RESULTS: In both groups, isotretinoin supplementation caused a dramatic increase in the circulating concentration of 13-CRA and its derivatives. Isotretinoin myotubularin related protein 11 Homo sapiens