| 1 |
34020817 | A non-affinity purification process for GMP production of prefusion-closed HIV-1 envelope trimers from clades A and C for clinical evaluation. | 2021 Jun 8 |
1 |
| 2 |
34469718 | Intramolecular quality control: HIV-1 envelope gp160 signal-peptide cleavage as a functional folding checkpoint. | 2021 Aug 31 |
1 |
| 3 |
34679128 | Engineering well-expressed, V2-immunofocusing HIV-1 envelope glycoprotein membrane trimers for use in heterologous prime-boost vaccine regimens. | 2021 Oct |
2 |
| 4 |
32522853 | Shedding-Resistant HIV-1 Envelope Glycoproteins Adopt Downstream Conformations That Remain Responsive to Conformation-Preferring Ligands. | 2020 Aug 17 |
1 |
| 5 |
30948772 | Inhibition of the thioredoxin system by PX-12 (1-methylpropyl 2-imidazolyl disulfide) impedes HIV-1 infection in TZM-bl cells. | 2019 Apr 4 |
3 |
| 6 |
31619555 | SOS and IP Modifications Predominantly Affect the Yield but Not Other Properties of SOSIP.664 HIV-1 Env Glycoprotein Trimers. | 2019 Dec 12 |
1 |
| 7 |
29470989 | Redox exchange of the disulfides of human two-domain CD4 regulates the conformational dynamics of each domain, providing insight into its mechanisms of control. | 2018 Mar 4 |
1 |
| 8 |
29729526 | Characterization of twin-cysteine motif in the V2-loop region of gp120 in primate lentiviruses. | 2018 Jun |
1 |
| 9 |
30021898 | SOSIP Changes Affect Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Conformation and CD4 Engagement. | 2018 Oct 1 |
1 |
| 10 |
26816344 | The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition. | 2016 |
1 |
| 11 |
27442017 | Generation and Characterization of a Bivalent HIV-1 Subtype C gp120 Protein Boost for Proof-of-Concept HIV Vaccine Efficacy Trials in Southern Africa. | 2016 |
1 |
| 12 |
27716795 | Effect of Glycosylation on an Immunodominant Region in the V1V2 Variable Domain of the HIV-1 Envelope gp120 Protein. | 2016 Oct |
1 |
| 13 |
25712564 | HIV-1 gp120 dimers decrease the overall affinity of gp120 preparations for CD4-induced ligands. | 2015 Apr |
3 |
| 14 |
25944298 | Conformational instability governed by disulfide bonds partitions the dominant from subdominant helper T-cell responses specific for HIV-1 envelope glycoprotein gp120. | 2015 Jun 9 |
3 |
| 15 |
26311893 | Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers. | 2015 Dec |
2 |
| 16 |
26458166 | Disulfide Sensitivity in the Env Protein Underlies Lytic Inactivation of HIV-1 by Peptide Triazole Thiols. | 2015 Dec 18 |
6 |
| 17 |
26690492 | Discovery of a Natural Defense Against HIV With Therapeutic Potential. | 2015 Oct-Dec |
1 |
| 18 |
26719247 | Native Conformation and Canonical Disulfide Bond Formation Are Interlinked Properties of HIV-1 Env Glycoproteins. | 2015 Dec 30 |
2 |
| 19 |
26719252 | Structure-Guided Redesign Increases the Propensity of HIV Env To Generate Highly Stable Soluble Trimers. | 2015 Dec 30 |
1 |
| 20 |
24920818 | Comprehensive analysis of contributions from protein conformational stability and major histocompatibility complex class II-peptide binding affinity to CD4+ epitope immunogenicity in HIV-1 envelope glycoprotein. | 2014 Sep 1 |
1 |
| 21 |
23210856 | Simple approach to assign disulfide connectivity using extracted ion chromatograms of electron transfer dissociation spectra. | 2013 Jan 15 |
1 |
| 22 |
23592978 | Allosteric modulation of the HIV-1 gp120-gp41 association site by adjacent gp120 variable region 1 (V1) N-glycans linked to neutralization sensitivity. | 2013 |
1 |
| 23 |
24146829 | Stabilizing exposure of conserved epitopes by structure guided insertion of disulfide bond in HIV-1 envelope glycoprotein. | 2013 |
2 |
| 24 |
22230366 | Thioredoxin-1 and protein disulfide isomerase catalyze the reduction of similar disulfides in HIV gp120. | 2012 Mar |
5 |
| 25 |
21689404 | A stabilized HIV-1 envelope glycoprotein trimer fused to CD40 ligand targets and activates dendritic cells. | 2011 Jun 20 |
1 |
| 26 |
22312332 | Structural Basis for Species Selectivity in the HIV-1 gp120-CD4 Interaction: Restoring Affinity to gp120 in Murine CD4 Mimetic Peptides. | 2011 |
1 |
| 27 |
20089653 | Influence of disulfide-stabilized structure on the specificity of helper T-cell and antibody responses to HIV envelope glycoprotein gp120. | 2010 Apr |
2 |
| 28 |
20458450 | Snapshot of the interaction between HIV envelope glycoprotein 120 and protein disulfide isomerase. | 2010 May 15 |
2 |
| 29 |
20538591 | Stabilization of HIV-1 gp120-CD4 receptor complex through targeted interchain disulfide exchange. | 2010 Aug 13 |
3 |
| 30 |
20943653 | Disulfide bond that constrains the HIV-1 gp120 V3 domain is cleaved by thioredoxin. | 2010 Dec 17 |
7 |
| 31 |
20956336 | Single-particle cryoelectron microscopy analysis reveals the HIV-1 spike as a tripod structure. | 2010 Nov 2 |
1 |
| 32 |
19038358 | Human glutaredoxin-1 catalyzes the reduction of HIV-1 gp120 and CD4 disulfides and its inhibition reduces HIV-1 replication. | 2009 Jun |
1 |
| 33 |
18237398 | The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion. | 2008 Jan 31 |
2 |
| 34 |
19018669 | High-affinity binding of southern African HIV type 1 subtype C envelope protein, gp120, to the CCR5 coreceptor. | 2008 Dec |
1 |
| 35 |
17092531 | Specific amino acids in the N-terminus of the gp41 ectodomain contribute to the stabilization of a soluble, cleaved gp140 envelope glycoprotein from human immunodeficiency virus type 1. | 2007 Mar 30 |
1 |
| 36 |
17525470 | The disulfide loop of gp41 is critical to the furin recognition site of HIV gp160. | 2007 Jun |
2 |
| 37 |
17640393 | Search for allosteric disulfide bonds in NMR structures. | 2007 Jul 20 |
1 |
| 38 |
19086590 | Computational comparison of T-cell epitopes of gp120 of Iranian HIV-1 with different subtypes of the virus. | 2007 Dec 1 |
1 |
| 39 |
15644496 | Glycosaminoglycans and protein disulfide isomerase-mediated reduction of HIV Env. | 2005 Apr |
1 |
| 40 |
15994775 | Evaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1. | 2005 Jul |
1 |
| 41 |
16182193 | Progress in targeting HIV-1 entry. | 2005 Aug 15 |
2 |
| 42 |
14592831 | Thiol/disulfide exchange is a prerequisite for CXCR4-tropic HIV-1 envelope-mediated T-cell fusion during viral entry. | 2004 Mar 1 |
1 |
| 43 |
12218052 | Protein-disulfide isomerase-mediated reduction of two disulfide bonds of HIV envelope glycoprotein 120 occurs post-CXCR4 binding and is required for fusion. | 2003 Jan 31 |
1 |
| 44 |
12719576 | Human immunodeficiency virus type 1 Env with an intersubunit disulfide bond engages coreceptors but requires bond reduction after engagement to induce fusion. | 2003 May |
1 |
| 45 |
12773488 | Folding of HIV-1 envelope glycoprotein involves extensive isomerization of disulfide bonds and conformation-dependent leader peptide cleavage. | 2003 Jun |
1 |
| 46 |
12923196 | Functional evolution of the HIV-1 envelope glycoprotein 120 association site of glycoprotein 41. | 2003 Oct 24 |
1 |
| 47 |
12163607 | Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1. | 2002 Sep |
1 |
| 48 |
12218051 | Inhibitors of protein-disulfide isomerase prevent cleavage of disulfide bonds in receptor-bound glycoprotein 120 and prevent HIV-1 entry. | 2002 Dec 27 |
4 |
| 49 |
11602730 | Fine definition of the epitope on the gp41 glycoprotein of human immunodeficiency virus type 1 for the neutralizing monoclonal antibody 2F5. | 2001 Nov |
1 |
| 50 |
10623724 | A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure. | 2000 Jan |
2 |