Title : SOS and IP Modifications Predominantly Affect the Yield but Not Other Properties of SOSIP.664 HIV-1 Env Glycoprotein Trimers.

Pub. Date : 2019 Dec 12

PMID : 31619555






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The prototypic design, designated BG505 SOSIP.664, incorporates an inter-subunit disulfide bond (SOS) to covalently link the gp120 and gp41 ectodomain (gp41ECTO) subunits and a point substitution, I559P (IP) to further stabilize the gp41ECTO components. Disulfides inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens