Disulfides

Envelope surface glycoprotein gp160, precursor ; Human immunodeficiency virus 1







47 Article(s)
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Pub. Year
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1 30429345 Conformational Differences between Functional Human Immunodeficiency Virus Envelope Glycoprotein Trimers and Stabilized Soluble Trimers. 2019 Feb 1 3
2 30971821 Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET. 2019 Apr 2
3 27716795 Effect of Glycosylation on an Immunodominant Region in the V1V2 Variable Domain of the HIV-1 Envelope gp120 Protein. 2016 Oct 1
4 25712564 HIV-1 gp120 dimers decrease the overall affinity of gp120 preparations for CD4-induced ligands. 2015 Apr 1
5 25944298 Conformational instability governed by disulfide bonds partitions the dominant from subdominant helper T-cell responses specific for HIV-1 envelope glycoprotein gp120. 2015 Jun 9 1
6 26458166 Disulfide Sensitivity in the Env Protein Underlies Lytic Inactivation of HIV-1 by Peptide Triazole Thiols. 2015 Dec 18 4
7 26577736 Effective isotope labeling of proteins in a mammalian expression system. 2015 1
8 26719247 Native Conformation and Canonical Disulfide Bond Formation Are Interlinked Properties of HIV-1 Env Glycoproteins. 2015 Dec 30 1
9 25026075 Glycosylation and disulfide bond analysis of transiently and stably expressed clade C HIV-1 gp140 trimers in 293T cells identifies disulfide heterogeneity present in both proteins and differences in O-linked glycosylation. 2014 Sep 5 1
10 23349893 HIV-1 fusion is blocked through binding of GB Virus C E2-derived peptides to the HIV-1 gp41 disulfide loop [corrected]. 2013 1
11 23618462 Forced virus evolution reveals functional crosstalk between the disulfide bonded region and membrane proximal ectodomain region of HIV-1 gp41. 2013 Apr 23 2
12 24146829 Stabilizing exposure of conserved epitopes by structure guided insertion of disulfide bond in HIV-1 envelope glycoprotein. 2013 1
13 22291921 Elicitation of neutralizing antibodies directed against CD4-induced epitope(s) using a CD4 mimetic cross-linked to a HIV-1 envelope glycoprotein. 2012 1
14 23085174 A DFT study on the interaction between adsorbed silver on C₆₀ and disulfide bond. 2012 Sep 1
15 21114338 Analysis of the disulfide bond arrangement of the HIV-1 envelope protein CON-S gp140 ΔCFI shows variability in the V1 and V2 regions. 2011 Feb 4 3
16 21117239 A mechanism by which binding of the broadly neutralizing antibody b12 unfolds the inner domain α1 helix in an engineered HIV-1 gp120. 2011 Feb 1
17 21121641 Discovery of a small molecule PDI inhibitor that inhibits reduction of HIV-1 envelope glycoprotein gp120. 2011 Mar 18 1
18 20230797 Role for the disulfide-bonded region of human immunodeficiency virus type 1 gp41 in receptor-triggered activation of membrane fusion function. 2010 Apr 16 1
19 20458450 Snapshot of the interaction between HIV envelope glycoprotein 120 and protein disulfide isomerase. 2010 May 15 1
20 20471426 Conformational characterization of aberrant disulfide-linked HIV-1 gp120 dimers secreted from overexpressing cells. 2010 Sep 1
21 20538591 Stabilization of HIV-1 gp120-CD4 receptor complex through targeted interchain disulfide exchange. 2010 Aug 13 8
22 19038358 Human glutaredoxin-1 catalyzes the reduction of HIV-1 gp120 and CD4 disulfides and its inhibition reduces HIV-1 replication. 2009 Jun 2
23 19583444 Computational model of the HIV-1 subtype A V3 loop: study on the conformational mobility for structure-based anti-AIDS drug design. 2009 Oct 1
24 18753405 Evolution rescues folding of human immunodeficiency virus-1 envelope glycoprotein GP120 lacking a conserved disulfide bond. 2008 Nov 1
25 17604546 Purified, proteolytically mature HIV type 1 SOSIP gp140 envelope trimers. 2007 Jun 1
26 16507315 Role of protein disulfide isomerase and other thiol-reactive proteins in HIV-1 envelope protein-mediated fusion. 2006 Jul 5 5
27 15725757 V3: HIV's switch-hitter. 2005 Feb 1
28 15169554 Evolution of the HIV-1 envelope glycoproteins with a disulfide bond between gp120 and gp41. 2004 Mar 9 5
29 15307920 Evolutionary repair of HIV type 1 gp41 with a kink in the N-terminal helix leads to restoration of the six-helix bundle structure. 2004 Jul 2
30 12719560 Redox-triggered infection by disulfide-shackled human immunodeficiency virus type 1 pseudovirions. 2003 May 1
31 12719576 Human immunodeficiency virus type 1 Env with an intersubunit disulfide bond engages coreceptors but requires bond reduction after engagement to induce fusion. 2003 May 2
32 12773488 Folding of HIV-1 envelope glycoprotein involves extensive isomerization of disulfide bonds and conformation-dependent leader peptide cleavage. 2003 Jun 1
33 12923196 Functional evolution of the HIV-1 envelope glycoprotein 120 association site of glycoprotein 41. 2003 Oct 24 1
34 14610200 Covalently linked human immunodeficiency virus type 1 gp120/gp41 is stably anchored in rhabdovirus particles and exposes critical neutralizing epitopes. 2003 Dec 2
35 12097589 Oligomeric and conformational properties of a proteolytically mature, disulfide-stabilized human immunodeficiency virus type 1 gp140 envelope glycoprotein. 2002 Aug 1
36 11413331 Functional analysis of the disulfide-bonded loop/chain reversal region of human immunodeficiency virus type 1 gp41 reveals a critical role in gp120-gp41 association. 2001 Jul 4
37 10623724 A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure. 2000 Jan 1
38 10799583 Variable-loop-deleted variants of the human immunodeficiency virus type 1 envelope glycoprotein can be stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits. 2000 Jun 1
39 9696864 Stabilization of human immunodeficiency virus type 1 envelope glycoprotein trimers by disulfide bonds introduced into the gp41 glycoprotein ectodomain. 1998 Sep 1
40 7589496 The complete Consensus V3 loop peptide of the envelope protein gp120 of HIV-1 shows pronounced helical character in solution. 1995 Oct 23 1
41 7504740 Presentation of native epitopes in the V1/V2 and V3 regions of human immunodeficiency virus type 1 gp120 by fusion glycoproteins containing isolated gp120 domains. 1994 Jan 1
42 1549912 Computer predictions of functional, topogenic, and antigenic domains in human immunodeficiency virus-2 envelope glycoprotein. 1992 Jan 2
43 1738091 Contribution of disulfide bonds in the carboxyl terminus of the human immunodeficiency virus type I gp120 glycoprotein to CD4 binding. 1992 3
44 1718344 Peptides mimicking selected disulfide loops in HIV-1 gp120, other than V3, do not elicit virus-neutralizing antibodies. 1991 Aug 2
45 1805558 Structure and function in recombinant HIV-1 gp120 and speculation about the disulfide bonding in the gp120 homologs of HIV-2 and SIV. 1991 1
46 2355006 Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells. 1990 Jun 25 1
47 2392685 Conserved sequence and structural elements in the HIV-1 principal neutralizing determinant. 1990 Aug 24 1