Title : Forced virus evolution reveals functional crosstalk between the disulfide bonded region and membrane proximal ectodomain region of HIV-1 gp41.

Pub. Date : 2013 Apr 23

PMID : 23618462






2 Functional Relationships(s)
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1 BACKGROUND: The disulfide-bonded region (DSR) of HIV-1 gp41 mediates association with gp120 and plays a role in transmission of receptor-induced conformational changes in gp120 to gp41 that activate membrane fusion function. Disulfides Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1
2 BACKGROUND: The disulfide-bonded region (DSR) of HIV-1 gp41 mediates association with gp120 and plays a role in transmission of receptor-induced conformational changes in gp120 to gp41 that activate membrane fusion function. Disulfides Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1