| 1 |
35452915 | Design, synthesis and biological evaluation of novel FAK inhibitors with better selectivity over IR than TAE226. | 2022 Jul |
4 |
| 2 |
34757216 | Design, synthesis, and biological evaluation of novel covalent inhibitors targeting focal adhesion kinase. | 2021 Dec 15 |
3 |
| 3 |
32784087 | Design, synthesis and biological evaluation of ring-fused pyrazoloamino pyridine/pyrimidine derivatives as potential FAK inhibitors. | 2020 Nov 1 |
1 |
| 4 |
32979460 | Mechano-stimulation initiated by extracellular adhesion and cationic conductance pathways influence astrocyte activation. | 2020 Nov 20 |
2 |
| 5 |
26549408 | Exploring the interaction between human focal adhesion kinase and inhibitors: a molecular dynamic simulation and free energy calculations. | 2016 Nov |
1 |
| 6 |
25625667 | Cytotoxic and radiosensitizing effects of FAK targeting in human glioblastoma cells in vitro. | 2015 Apr |
4 |
| 7 |
23845217 | Synthesis of novel diarylamino-1,3,5-triazine derivatives as FAK inhibitors with anti-angiogenic activity. | 2013 Aug 15 |
1 |
| 8 |
22705303 | Oral administration of FAK inhibitor TAE226 inhibits the progression of peritoneal dissemination of colorectal cancer. | 2012 Jul 13 |
1 |
| 9 |
22766511 | Anti-tumor effect of a novel FAK inhibitor TAE226 against human oral squamous cell carcinoma. | 2012 Nov |
5 |
| 10 |
21338601 | Anti-tumor effect in human breast cancer by TAE226, a dual inhibitor for FAK and IGF-IR in vitro and in vivo. | 2011 May 1 |
4 |
| 11 |
21454698 | Focal adhesion kinase (FAK) binds RET kinase via its FERM domain, priming a direct and reciprocal RET-FAK transactivation mechanism. | 2011 May 13 |
3 |
| 12 |
19784551 | TAE226-mediated inhibition of focal adhesion kinase interferes with tumor angiogenesis and vasculogenesis. | 2010 Dec |
2 |
| 13 |
20441998 | Usage of heparan sulfate, integrins, and FAK in HPV16 infection. | 2010 Jul 20 |
1 |
| 14 |
19729215 | 3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226. | 2009 Sep |
4 |
| 15 |
17849451 | TAE226-induced apoptosis in breast cancer cells with overexpressed Src or EGFR. | 2008 Mar |
5 |
| 16 |
18259944 | TAE226 inhibits human neuroblastoma cell survival. | 2008 Mar |
2 |
| 17 |
18628478 | Dual tyrosine kinase inhibitor for focal adhesion kinase and insulin-like growth factor-I receptor exhibits anticancer effect in esophageal adenocarcinoma in vitro and in vivo. | 2008 Jul 15 |
3 |
| 18 |
19020730 | TAE226, a dual inhibitor for FAK and IGF-IR, has inhibitory effects on mTOR signaling in esophageal cancer cells. | 2008 Dec |
3 |
| 19 |
19030106 | Crystal structures of the FAK kinase in complex with TAE226 and related bis-anilino pyrimidine inhibitors reveal a helical DFG conformation. | 2008 |
4 |
| 20 |
17219439 | A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth. | 2007 Jun |
3 |
| 21 |
17431114 | Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo. | 2007 Apr |
6 |
| 22 |
18006843 | Therapeutic efficacy of a novel focal adhesion kinase inhibitor TAE226 in ovarian carcinoma. | 2007 Nov 15 |
5 |