Title : Oral administration of FAK inhibitor TAE226 inhibits the progression of peritoneal dissemination of colorectal cancer.

Pub. Date : 2012 Jul 13

PMID : 22705303






1 Functional Relationships(s)
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Protein Name
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1 In vitro, TAE226 greatly inhibited the proliferation and migration of HCT116 colon cancer cells, while their adhesion on the matrix surface was minimally inhibited when FAK activity and expression was suppressed by TAE226 and siRNA. TAE226 protein tyrosine kinase 2 Homo sapiens