Tyrosine

interferon alpha 1 ; Homo sapiens







150 Article(s)
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51 15087447 Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells. 2004 Jun 18 1
52 15166220 Role of the interleukin (IL)-28 receptor tyrosine residues for antiviral and antiproliferative activity of IL-29/interferon-lambda 1: similarities with type I interferon signaling. 2004 Jul 30 3
53 15175343 STAT2 nuclear trafficking. 2004 Sep 17 1
54 15296650 Effects of the hepatitis C virus core protein on innate cellular defense pathways. 2004 Jul 1
55 15302890 Induction of genes mediating interferon-dependent extracellular trap formation during neutrophil differentiation. 2004 Oct 15 1
56 15467722 Amplification of IFN-alpha-induced STAT1 activation and inflammatory function by Syk and ITAM-containing adaptors. 2004 Nov 2
57 15542633 Conventional protein kinase C inhibition prevents alpha interferon-mediated hepatitis C virus replicon clearance by impairing STAT activation. 2004 Dec 1
58 12600939 Protein ISGylation modulates the JAK-STAT signaling pathway. 2003 Feb 15 1
59 12610111 The STAT2 activation process is a crucial target of Sendai virus C protein for the blockade of alpha interferon signaling. 2003 Mar 1
60 12789268 Atypical expression of ErbB3 in myeloma cells: cross-talk between ErbB3 and the interferon-alpha signaling complex. 2003 Jun 5 2
61 12792788 Synergistic growth inhibitory effects of interferon-alpha and lovastatin on bcr-abl positive leukemic cells. 2003 Jul 1
62 12804067 Synergistic antiviral activity of human interferon combinations in the hepatitis C virus replicon system. 2003 May 1
63 12883649 Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation. 2003 Sep 1
64 11802163 IFN-Stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoff. 2002 Feb 1
65 11821064 Sendai virus C protein impairs both phosphorylation and dephosphorylation processes of Stat1. 2002 Jan 30 3
66 11886239 Dephosphorylation failure of tyrosine-phosphorylated STAT1 in IFN-stimulated Sendai virus C protein-expressing cells. 2002 Feb 15 2
67 12040445 Direct signal transduction via functional interferon-alphabeta receptors in CD34+ hematopoietic stem cells. 2002 Jun 1
68 12051728 Involvement of IL-1beta and IL-10 in IFN-alpha-mediated antiviral gene induction in human hepatoma cells. 2002 Jun 7 2
69 12105218 STAT3 activation by type I interferons is dependent on specific tyrosines located in the cytoplasmic domain of interferon receptor chain 2c. Activation of multiple STATS proceeds through the redundant usage of two tyrosine residues. 2002 Sep 20 5
70 12421984 Anticancer activity of sodium stibogluconate in synergy with IFNs. 2002 Nov 15 2
71 11150296 Arginine/lysine-rich structural element is involved in interferon-induced nuclear import of STATs. 2001 May 11 1
72 11162588 Frap-dependent serine phosphorylation of IRS-1 inhibits IRS-1 tyrosine phosphorylation. 2001 Jan 26 2
73 11248056 A transcriptional corepressor of Stat1 with an essential LXXLL signature motif. 2001 Mar 13 2
74 11277596 Analgesic domains of interferon-alpha. 2001 Mar 26 4
75 11301323 The WD motif-containing protein receptor for activated protein kinase C (RACK1) is required for recruitment and activation of signal transducer and activator of transcription 1 through the type I interferon receptor. 2001 Jun 22 2
76 11408801 Interferon alpha induction of Stat1 and Stat2 and their prognostic significance in carcinoid tumors. 2001 1
77 11473581 Cross talk of the interferon-alpha/beta signalling complex with gp130 for effective interleukin-6 signalling. 2001 Jul 1
78 11476770 Members of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway are present and active in human sperm. 2001 Aug 1
79 11513540 Detection of intracellular phosphorylated STAT-4 by flow cytometry. 2001 Sep 1
80 10657627 IFN-gamma activates the C3G/Rap1 signaling pathway. 2000 Feb 15 1
81 10666284 Sendai virus blocks alpha interferon signaling to signal transducers and activators of transcription. 2000 Mar 3
82 10753717 Paramyxoviridae use distinct virus-specific mechanisms to circumvent the interferon response. 2000 Apr 10 1
83 10777558 Distinct mechanisms of STAT phosphorylation via the interferon-alpha/beta receptor. Selective inhibition of STAT3 and STAT5 by piceatannol. 2000 Apr 28 2
84 10803933 The activation of intracellular tyrosine kinases by interferon-alpha (IFNalpha) correlates with its antiproliferative activity in B-lymphoid cell lines, but not in B-cell chronic lymphocytic leukemia patients. 2000 Mar 4
85 10900338 Distinct domains of IFNalpha mediate immune and analgesic effects respectively. 2000 Aug 1 4
86 10918594 IFN-beta induces serine phosphorylation of Stat-1 in Ewing's sarcoma cells and mediates apoptosis via induction of IRF-1 and activation of caspase-7. 2000 Jul 13 1
87 10982828 Role of the Stat4 N domain in receptor proximal tyrosine phosphorylation. 2000 Oct 1
88 11956564 [Distinct structural bases of the immunoregulatory and central analgesic effects of IFNalpha]. 2000 Jun 1
89 9872990 Activation of a CrkL-stat5 signaling complex by type I interferons. 1999 Jan 8 2
90 10029571 Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma- induced genes by suppressing tyrosine phosphorylation of STAT1. 1999 Mar 1 3
91 10068671 Interferon-alpha activates multiple STAT proteins and upregulates proliferation-associated IL-2Ralpha, c-myc, and pim-1 genes in human T cells. 1999 Mar 15 1
92 10098730 Butyrate augments interferon-alpha-induced S phase accumulation and persistent tyrosine phosphorylation of cdc2 in K562 cells. 1999 Mar 2
93 10428508 CrkL and CrkII participate in the generation of the growth inhibitory effects of interferons on primary hematopoietic progenitors. 1999 Aug 1
94 10488146 JAK1-dependent phosphorylation of insulin receptor substrate-1 (IRS-1) is inhibited by IRS-1 serine phosphorylation. 1999 Sep 24 4
95 10490982 IFN-alpha activates Stat6 and leads to the formation of Stat2:Stat6 complexes in B cells. 1999 Oct 1 2
96 10586107 [Interferon signaling pathways]. 1999 Nov 2
97 9501047 The antiviral action of interferon is potentiated by removal of the conserved IRTAM domain of the IFNAR1 chain of the interferon alpha/beta receptor: effects on JAK-STAT activation and receptor down-regulation. 1998 Mar 1 4
98 9531615 Prolonged STAT1 activation related to the growth arrest of malignant lymphoma cells by interferon-alpha. 1998 Apr 15 1
99 9581833 Prolactin activates Stat1 but does not antagonize Stat1 activation and growth inhibition by type I interferons in human breast cancer cells. 1998 May 1 4
100 9677371 Identification of amino acid residues critical for the Src-homology 2 domain-dependent docking of Stat2 to the interferon alpha receptor. 1998 Jul 31 3