Steroids

cytochrome P450 family 11 subfamily A member 1 ; Homo sapiens







144 Article(s)
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51 19116262 Metabolism of vitamin d2 to 17,20,24-trihydroxyvitamin d2 by cytochrome p450scc (CYP11A1). 2009 Apr 2
52 19662162 Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics. 2009 Aug 1
53 19824542 [Construction and characteristics of transgenic tobacco Nicotiana tabacum L. plants expressing CYP11A1 cDNA encoding cytochrome P450scc]. 2009 Sep 2
54 19846611 The spontaneous Ala147Thr amino acid substitution within the translocator protein influences pregnenolone production in lymphomonocytes of healthy individuals. 2009 Dec 1
55 16730372 Human LBP-32/MGR is a repressor of the P450scc in human choriocarcinoma cell line JEG-3. 2007 Feb-Mar 1
56 17216615 Human CYP11A1 promoter drives Cre recombinase expression in the brain in addition to adrenals and gonads. 2007 Feb 2
57 17400813 Expression of molecular equivalent of hypothalamic-pituitary-adrenal axis in adult retinal pigment epithelium. 2007 Apr 1
58 17594537 Transcriptional regulation of human CYP11A1 in gonads and adrenals. 2007 Jul 1
59 17709382 Histone deacetylase inhibitors reduce steroidogenesis through SCF-mediated ubiquitination and degradation of steroidogenic factor 1 (NR5A1). 2007 Oct 1
60 17975261 Steroidogenic factor 1/adrenal 4 binding protein transforms human bone marrow mesenchymal cells into steroidogenic cells. 2007 Nov 1
61 18001058 Steroidogenic acute regulatory (StAR) protein and cholesterol side-chain cleavage (P450scc) as molecular and cellular targets for 17alpha-ethynylestradiol in salmon previtellogenic oocytes. 2007 Dec 2
62 16650473 Alteration of steroidogenesis in H295R cells by organic sediment contaminants and relationships to other endocrine disrupting effects. 2006 Aug 1
63 16872679 Cytochrome P450s and cholesterol homeostasis. 2006 Dec 1
64 17178901 A systematic assessment of common genetic variation in CYP11A and risk of breast cancer. 2006 Dec 15 1
65 15471945 LBP proteins modulate SF1-independent expression of P450scc in human placental JEG-3 cells. 2005 Feb 1
66 15507506 Homozygous disruption of P450 side-chain cleavage (CYP11A1) is associated with prematurity, complete 46,XY sex reversal, and severe adrenal failure. 2005 Jan 1
67 15747502 Autoantibodies against CYP2D6 and other drug-metabolizing enzymes in autoimmune hepatitis type 2. 2005 1
68 15026180 Function of Cyp11a1 in animal models. 2004 Feb 27 3
69 15054879 Microsatellite polymorphism of steroid hormone synthesis gene CYP11A1 is associated with advanced prostate cancer. 2004 May 20 2
70 15126571 Large-scale analysis of the relationship between CYP11A promoter variation, polycystic ovarian syndrome, and serum testosterone. 2004 May 2
71 15181009 Stripping down the mitochondrial cholesterol hydroxylase system, a kinetics study. 2004 Aug 13 1
72 15344917 Neurosteroids: the StAR protein in the brain. 2004 Sep 1
73 12556907 Cloning of murine TReP-132, a novel transcription factor expressed in brain regions involved in behavioral and psychiatric disorders. 2003 Jan 1
74 12654006 Critical role of the plasma membrane for expression of mammalian mitochondrial side chain cleavage activity in yeast. 2003 Apr 1
75 14576461 Transcriptional regulation of CYP11A1. 2003 1
76 14637024 The F-G loop region of cytochrome P450scc (CYP11A1) interacts with the phospholipid membrane. 2003 Oct 31 1
77 11869873 Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line. 2002 Apr 1
78 12092456 Autoantibodies in autoimmune polyendocrine syndrome type II. 2002 Jun 1
79 12101186 The transcriptional regulating protein of 132 kDa (TReP-132) enhances P450scc gene transcription through interaction with steroidogenic factor-1 in human adrenal cells. 2002 Oct 18 1
80 12161514 Compound heterozygous mutations in the cholesterol side-chain cleavage enzyme gene (CYP11A) cause congenital adrenal insufficiency in humans. 2002 Aug 1
81 12530639 The life cycle of the steroidogenic acute regulatory (StAR) protein: from transcription through proteolysis. 2002 Nov 1
82 12530663 Function of the transcriptional regulating protein of 132 kDa (TReP-132) on human P450scc gene expression. 2002 Nov 2
83 11297612 Screening for mutations in the steroidogenic acute regulatory protein and steroidogenic factor-1 genes, and in CYP11A and dosage-sensitive sex reversal-adrenal hypoplasia gene on the X chromosome, gene-1 (DAX-1), in hyperandrogenic hirsute women. 2001 Apr 2
84 11349124 A novel zinc finger protein TReP-132 interacts with CBP/p300 to regulate human CYP11A1 gene expression. 2001 Sep 7 1
85 11502818 Heterozygous mutation in the cholesterol side chain cleavage enzyme (p450scc) gene in a patient with 46,XY sex reversal and adrenal insufficiency. 2001 Aug 1
86 11726279 Adrenodoxin-cytochrome P450scc interaction as revealed by EPR spectroscopy: comparison with the putidaredoxin-cytochrome P450cam system. 2001 Dec 1
87 11806292 Structure, function and regulation of the mitochondrial peripheral-type benzodiazepine receptor. 2001 Sep-Oct 1
88 10644752 Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc. 2000 Jan 28 1
89 10413522 Complex formation in vesicle-reconstituted mitochondrial cytochrome P450 systems (CYP11A1 and CYP11B1) as evidenced by rotational diffusion experiments using EPR and ST-EPR. 1999 Jul 20 1
90 10416690 Synthesis of steroids in pancreas: evidence of cytochrome P-450scc activity. 1999 Jul 2
91 10418987 Molecular pathology and mechanism of action of the steroidogenic acute regulatory protein, StAR. 1999 Apr-Jun 1
92 10419010 Cell-type specificity of human CYP11A1 TATA box. 1999 Apr-Jun 1
93 10446912 Activator protein-2 mediates transcriptional activation of the CYP11A1 gene by interaction with Sp1 rather than binding to DNA. 1999 Aug 1
94 10549824 Expression of cytochrome P450scc mRNA in the hippocampus of patients with temporal lobe epilepsy. 1999 Sep 29 3
95 10570260 Specialized ability of thymic epithelial cells to mediate positive selection does not require expression of the steroidogenic enzyme p450scc. 1999 Dec 1 1
96 9468515 Regulation of the human P450scc gene by steroidogenic factor 1 is mediated by CBP/p300. 1998 Feb 20 2
97 9511181 Genetic linkage mapping of the CYP11A1 gene encoding the cholesterol side-chain cleavage P450scc close to the CYP1A1 gene and D15S204 in the chromosome 15q22.33-q23 region. 1998 Feb 1
98 9578606 Expression of catalytically active human cytochrome p450scc in Escherichia coli and mutagenesis of isoleucine-462. 1998 May 1 2
99 18406240 Current developments in the molecular genetics of the polycystic ovary syndrome. 1998 Feb 1
100 9029710 Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis. 1997 Jan 1