Title : The transcriptional regulating protein of 132 kDa (TReP-132) enhances P450scc gene transcription through interaction with steroidogenic factor-1 in human adrenal cells.

Pub. Date : 2002 Oct 18

PMID : 12101186






1 Functional Relationships(s)
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1 The human P450scc gene is regulated by the tissue-specific orphan nuclear receptor, steroidogenic factor-1 (SF-1), which plays a key role in several physiologic processes including steroid synthesis, adrenal and gonadal development, and sexual differentiation. Steroids cytochrome P450 family 11 subfamily A member 1 Homo sapiens