Guanosine Triphosphate

ras homolog family member A ; Homo sapiens







358 Article(s)
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301 11058585 Characterization of p190RhoGEF, a RhoA-specific guanine nucleotide exchange factor that interacts with microtubules. 2001 Feb 16 2
302 11342655 Role of p190RhoGAP in beta 2 integrin regulation of RhoA in human neutrophils. 2001 May 15 6
303 11373293 Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA. 2001 Jul 20 1
304 11401849 Regulation by GDI of RhoA/Rho-kinase-induced Ca2+ sensitization of smooth muscle myosin II. 2001 Jul 4
305 10639096 Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II. 2000 Jan 15 1
306 10716190 Human RhoA/RhoGDI complex expressed in yeast: GTP exchange is sufficient for translocation of RhoA to liposomes. 2000 Feb 13
307 10748207 An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism. 2000 Jun 16 1
308 10931345 The RhoGAP activity of the Yersinia pseudotuberculosis cytotoxin YopE is required for antiphagocytic function and virulence. 2000 Aug 1
309 10934226 The Rho family guanine nucleotide exchange factor Vav-2 regulates the development of cell-mediated cytotoxicity. 2000 Aug 7 1
310 10970850 Ezrin function is required for ROCK-mediated fibroblast transformation by the Net and Dbl oncogenes. 2000 Sep 1 2
311 11125205 Regulation of the epithelial Na(+) /H(+) exchanger isoform by the cytoskeleton. 2000 1
312 10037681 Interaction of the small G protein RhoA with the C terminus of human phospholipase D1. 1999 Mar 5 1
313 10213513 Overexpression of small GTP-binding protein RhoA promotes invasion of tumor cells. 1999 Apr 15 2
314 10388627 Biochemical and crystallographic characterization of a Rho effector domain of the protein serine/threonine kinase N in a complex with RhoA. 1999 Jun 15 1
315 10411652 Phosphoinositide-dependent activation of Rho A involves partial opening of the RhoA/Rho-GDI complex. 1999 Jun 7
316 10489445 How RhoGDI binds Rho. 1999 Sep 1
317 9535835 Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7. 1998 Apr 10 1
318 9545299 Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue. 1998 Apr 17 1
319 9548756 Regulation of RhoA GTP hydrolysis by the GTPase-activating proteins p190, p50RhoGAP, Bcr, and 3BP-1. 1998 Apr 14 4
320 9588200 Rho protein inhibition blocks protein kinase C translocation and activation. 1998 Apr 28 1
321 9624180 Gbeta gamma-independent coupling of alpha2-adrenergic receptor to p21(rhoA) in preadipocytes. 1998 Jun 19 1
322 9635436 The small GTP-binding protein RhoA regulates a delayed rectifier potassium channel. 1998 Jun 12 2
323 9649803 Regulation of phospholipase C delta 1 activity by GTP-binding proteins: rhoA as an inhibitory modulator. 1998 May 1
324 18521231 Lip, a human gene detected by transfection of DNA from a human liposarcoma encodes a protein with homology to regulators of small g proteins. 1998 1
325 9029013 Analysis of CD9, CD32 and p67 signalling: use of degranulated platelets indicates direct involvement of CD9 and p67 in integrin activation. 1997 Feb 1
326 9030542 Reversible translocation of phosphoinositide 3-kinase to the cytoskeleton of ADP-aggregated human platelets occurs independently of Rho A and without synthesis of phosphatidylinositol (3,4)-bisphosphate. 1997 Feb 21 1
327 9143362 Inhibition of GTP gamma S-dependent phospholipase D and Rho membrane association by calphostin is independent of protein kinase C catalytic activity. 1997 May 1 1
328 9150952 Protein expression changes associated with radiation-induced neoplastic progression of human prostate epithelial cells. 1997 Mar-Apr 1
329 9204916 Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities. 1997 Jul 15 1
330 9338791 Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue. 1997 Oct 16 1
331 9398081 Lovastatin induces apoptosis by inhibiting mitotic and post-mitotic events in cultured mesangial cells. 1997 Oct 30 1
332 9407060 Structural determinants required for the interaction between Rho GTPase and the GTPase-activating domain of p190. 1997 Dec 26 1
333 9451818 The GTP-binding protein Rho. 1997 Nov 1
334 8584934 Role of Rho in chemoattractant-activated leukocyte adhesion through integrins. 1996 Feb 16 1
335 8599934 Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes. 1996 Feb 1 8
336 8626786 Regulation of membrane-bound phospholipase D by protein kinase C in HL60 cells. Synergistic action of small GTP-binding protein RhoA. 1996 Feb 23 2
337 8674536 Reconstitution of GTP-gamma-S-dependent phospholipase D activity with ARF, RhoA, and a soluble 36-kDa protein. 1996 Jun 3 1
338 8681427 Biochemistry and cell biology of phospholipase D in human neutrophils. 1996 May 24 1
339 8682874 Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. 1996 Jun 1
340 8769096 Interaction of the Rho family small G proteins with kinectin, an anchoring protein of kinesin motor. 1996 Aug 5 1
341 8816443 The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton. 1996 Oct 3
342 8939998 RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG. 1996 Nov 29 1
343 9145335 Differential expression of protein kinase C isozymes and small GTP-binding proteins during HL60 cell differentiation by retinoic acid and cyclic AMP: relation with phospholipase D (PLD) activation. 1996-1997 1
344 21544341 Signaling pathways regulated by Rho-like proteins. 1996 Jan 1
345 7479768 Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family. 1995 Oct 24 2
346 7539118 Regulation of Ras-related RhoB protein expression during the cell cycle. 1995 May 18 1
347 7592961 RhoA and a cytosolic 50-kDa factor reconstitute GTP gamma S-dependent phospholipase D activity in human neutrophil subcellular fractions. 1995 Nov 10 2
348 7721742 Regulation of phospholipase D in HL60 cells. Evidence for a cytosolic phospholipase D. 1995 Apr 14 2
349 7779100 Activation of membrane-bound phospholipase D by protein kinase C in HL60 cells: synergistic action of a small GTP-binding protein RhoA. 1995 Jun 6 1
350 7852400 Low molecular weight GTP-binding proteins in HL-60 granulocytes. Assessment of the role of ARF and of a 50-kDa cytosolic protein in phospholipase D activation. 1995 Feb 17 1