Title : Structural determinants required for the interaction between Rho GTPase and the GTPase-activating domain of p190.

Pub. Date : 1997 Dec 26

PMID : 9407060






1 Functional Relationships(s)
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1 To understand the mechanism of GAP-catalyzed GTP hydrolysis of Rho GTPases, we have studied the interaction between RhoA and p190, the RasGAP binding phosphoprotein which has been implicated as a Rho-specific GAP, by delineating the structural determinants of RhoA and p190 GAP domain (p190GD) that are involved in their functional coupling. Guanosine Triphosphate ras homolog family member A Homo sapiens