Tetracycline

tumor protein p53 ; Homo sapiens







56 Article(s)
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1 32942535 Distinct TP53 Mutation Types Exhibit Increased Sensitivity to Ferroptosis Independently of Changes in Iron Regulatory Protein Activity. 2020 Sep 15 2
2 27698449 Cr(VI) induces premature senescence through ROS-mediated p53 pathway in L-02 hepatocytes. 2016 Oct 4 2
3 25444916 Curcumin promotes apoptosis by activating the p53-miR-192-5p/215-XIAP pathway in non-small cell lung cancer. 2015 Feb 1 2
4 18801387 Generalized tetracycline induced Cre recombinase expression through the ROSA26 locus of recombinant mice. 2009 Jan 15 1
5 19602589 The G protein-coupled receptor 87 is necessary for p53-dependent cell survival in response to genotoxic stress. 2009 Aug 1 1
6 19639960 The cell line secretome, a suitable tool for investigating proteins released in vivo by tumors: application to the study of p53-modulated proteins secreted in lung cancer cells. 2009 Oct 1
7 18003626 The role of p53 in DNA damage-mediated cytotoxicity overrides its ability to regulate nucleotide excision repair in human fibroblasts. 2008 Jan 1
8 18267949 p53-dependent global nucleotide excision repair of cisplatin-induced intrastrand cross links in human cells. 2008 Mar 1
9 17210690 DNA replication licensing factor minichromosome maintenance deficient 5 rescues p53-mediated growth arrest. 2007 Jan 1 1
10 17283151 p53 enhances gefitinib-induced growth inhibition and apoptosis by regulation of Fas in non-small cell lung cancer. 2007 Feb 1 2
11 17363597 A single nucleotide polymorphism in the MDM2 gene disrupts the oscillation of p53 and MDM2 levels in cells. 2007 Mar 15 4
12 21603516 Inhibition of Erythroleukemia Cell Growth by Triplex-forming RNAs. 2007 Summer 5
13 16624812 Excess HDM2 impacts cell cycle and apoptosis and has a selective effect on p53-dependent transcription. 2006 Jun 23 2
14 16966095 Exit from arsenite-induced mitotic arrest is p53 dependent. 2006 Sep 1
15 15998635 Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs. 2005 Aug 26 2
16 16120440 Radiation response and cell cycle regulation of p53 rescued malignant keratinocytes. 2005 Oct 15 3
17 14990579 Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation. 2004 May 7 3
18 15087457 DNA damage induces p53-dependent BRCA1 nuclear export. 2004 Jul 2 1
19 15111320 Beta-catenin simultaneously induces activation of the p53-p21WAF1 pathway and overexpression of cyclin D1 during squamous differentiation of endometrial carcinoma cells. 2004 May 1
20 15319038 Adenovirus vector-mediated doxycycline-inducible RNA interference. 2004 Aug 1
21 12624953 [Dominant-negative inactivation of p53: the effect of the proportion between trans-dominant inhibitor and its target]. 2003 Jan-Feb 2
22 12702563 Molecular imaging of protein-protein interactions: controlled expression of p53 and large T-antigen fusion proteins in vivo. 2003 Apr 15 1
23 12096336 Novel gain of function activity of p53 mutants: activation of the dUTPase gene expression leading to resistance to 5-fluorouracil. 2002 Jul 11 2
24 12234998 p53 controls global nucleotide excision repair of low levels of structurally diverse benzo(g)chrysene-DNA adducts in human fibroblasts. 2002 Sep 15 1
25 12374798 Transcriptional activation of the MUC2 gene by p53. 2002 Dec 13 1
26 12439598 Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines. 2002 Nov 1
27 11158294 p53 down-regulates CHK1 through p21 and the retinoblastoma protein. 2001 Feb 1
28 11350911 Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents. 2001 May 2
29 11373271 Overexpressed human RAD50 exhibits cell death in a p21(WAF1/CIP1)-dependent manner: its potential utility in local gene therapy of tumor. 2001 May 1
30 11375983 Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1. 2001 Aug 10 2
31 11434920 Alterations in expression of E2F-1 and E2F-responsive genes by RB, p53 and p21(Sdi1/WAF1/Cip1) expression. 2001 Jun 29 1
32 11489880 Caffeine sensitizes human H358 cell line to p53-mediated apoptosis by inducing mitochondrial translocation and conformational change of BAX protein. 2001 Oct 19 2
33 11536301 Reduction of wild type p53 function confers a hormone resistant phenotype on LNCaP prostate cancer cells. 2001 Sep 15 1
34 11593387 p53 and its homologues, p63 and p73, induce a replicative senescence through inactivation of NF-Y transcription factor. 2001 Sep 13 1
35 11892838 Cell cycle arrest is sufficient for p53-mediated tumor regression. 2001 Nov 2
36 11027272 Proapoptotic p53-interacting protein 53BP2 is induced by UV irradiation but suppressed by p53. 2000 Nov 3
37 11108661 Induced expression of dominant-negative c-jun downregulates NFkappaB and AP-1 target genes and suppresses tumor phenotype in human keratinocytes. 2000 Nov 1
38 9891091 Thymidylate synthase protein and p53 mRNA form an in vivo ribonucleoprotein complex. 1999 Feb 1
39 9927213 A tumor specific single chain antibody dependent gene expression system. 1999 Jan 14 1
40 10467417 Anti-apoptotic activity of p53 maps to the COOH-terminal domain and is retained in a highly oncogenic natural mutant. 1999 Aug 19 1
41 10531402 Modulation of cisplatinum cytotoxicity by p53: effect of p53-mediated apoptosis and DNA repair. 1999 Nov 1
42 10588737 Identification and classification of p53-regulated genes. 1999 Dec 7 1
43 9467956 p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells. 1998 Jan 22 1
44 9492043 p53 regulates insulin-like growth factor-I (IGF-I) receptor expression and IGF-I-induced tyrosine phosphorylation in an osteosarcoma cell line: interaction between p53 and Sp1. 1998 Mar 1
45 9575175 Serine/threonine protein phosphatase type 5 acts upstream of p53 to regulate the induction of p21(WAF1/Cip1) and mediate growth arrest. 1998 May 15 2
46 9661919 Positivity of the proliferation marker Ki-67 in noncycling cells. 1998 Jul 1
47 9766676 Inhibition of tumor cell growth by RTP/rit42 and its responsiveness to p53 and DNA damage. 1998 Oct 1 3
48 9772303 Up-regulation of p53 by antisense expression of HPV18 E6 oncogene does not influence the level of MN/CA IX tumor-associated protein in HeLa cervical carcinoma cells. 1998 Nov 1
49 10023442 Transcriptional regulation and induction of apoptosis: implications for the use of monomeric p53 variants in gene therapy. 1998 Dec 1
50 11245004 [A study on the tumor suppressing effect of a specific point mutant p53 minigene in the expression regulated model with a tetracycline-transactivative response promoter]. 1998 Oct 4