Title : Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1.

Pub. Date : 2001 Aug 10

PMID : 11375983






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 When ectopic wild-type p53 expression was induced to a physiologically relevant level in "tet-off" cultured cells in which p53 expression was tightly regulated by tetracycline, it was found that POLD1 steady-state mRNA was repressed by about 65%. Tetracycline tumor protein p53 Homo sapiens
2 When ectopic wild-type p53 expression was induced to a physiologically relevant level in "tet-off" cultured cells in which p53 expression was tightly regulated by tetracycline, it was found that POLD1 steady-state mRNA was repressed by about 65%. Tetracycline tumor protein p53 Homo sapiens