Title : Radiation response and cell cycle regulation of p53 rescued malignant keratinocytes.

Pub. Date : 2005 Oct 15

PMID : 16120440






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 To study the function of p53 in a keratinocyte background, a tetracycline-controlled p53 transgene was introduced into a human SCC cell line (SCC15), lacking endogenous p53. Tetracycline tumor protein p53 Homo sapiens
2 To study the function of p53 in a keratinocyte background, a tetracycline-controlled p53 transgene was introduced into a human SCC cell line (SCC15), lacking endogenous p53. Tetracycline tumor protein p53 Homo sapiens
3 Conditional expression of wild-type p53 protein upon withdrawal of tetracycline was accompanied with increased expression of p21(WAF1/Cip1) resulting in reduced cell proliferation. Tetracycline tumor protein p53 Homo sapiens