| 1 |
31809756 | Sesamin suppresses NSCLC cell proliferation and induces apoptosis via Akt/p53 pathway. | 2020 Jan 15 |
1 |
| 2 |
32722075 | Tamoxifen and the PI3K Inhibitor: LY294002 Synergistically Induce Apoptosis and Cell Cycle Arrest in Breast Cancer MCF-7 Cells. | 2020 Jul 24 |
1 |
| 3 |
32742376 | TP53 mutation influences the efficacy of treatment of colorectal cancer cell lines with a combination of sirtuin inhibitors and chemotherapeutic agents. | 2020 Aug |
1 |
| 4 |
29207130 | Ethanol extract from Cnidium monnieri (L.) Cusson induces cell cycle arrest and apoptosis via regulation of the p53‑independent pathway in HepG2 and Hep3B hepatocellular carcinoma cells. | 2018 Feb |
1 |
| 5 |
27545131 | [Icariin reduces S-nitrosogultathione induced endothelial cell apoptosis through modulating AKT/P53 pathway]. | 2016 Aug 24 |
1 |
| 6 |
26223322 | Mutant p53 promotes ovarian cancer cell adhesion to mesothelial cells via integrin β4 and Akt signals. | 2015 Jul 30 |
1 |
| 7 |
25078983 | PI3K/Akt/uncoupling protein 2 signaling pathway may be involved in cell senescence and apoptosis induced by angiotensin II in human vascular endothelial cells. | 2014 Oct |
1 |
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22172953 | The phosphoinositide 3-kinase inhibitor LY294002, decreases aminoacyl-tRNA synthetases, chaperones and glycolytic enzymes in human HT-29 colorectal cancer cells. | 2012 Feb 16 |
4 |
| 9 |
20198331 | Targeting the cell cycle and the PI3K pathway: a possible universal strategy to reactivate innate tumor suppressor programmes in cancer cells. | 2010 Apr |
1 |
| 10 |
20418912 | Essential role of PI3-kinase pathway in p53-mediated transcription: Implications in cancer chemotherapy. | 2010 Jun 24 |
3 |
| 11 |
19457607 | Arsenic trioxide induces apoptosis and G2/M phase arrest by inducing Cbl to inhibit PI3K/Akt signaling and thereby regulate p53 activation. | 2009 Nov 1 |
1 |
| 12 |
19567200 | PI3K/AKT mediated p53 down-regulation participates in CpG DNA inhibition of spontaneous B cell apoptosis. | 2009 Jun |
1 |
| 13 |
18330473 | Class I phosphatidylinositol 3-kinase inhibitor LY294002 activates autophagy and induces apoptosis through p53 pathway in gastric cancer cell line SGC7901. | 2008 Mar |
5 |
| 14 |
18358096 | LY294002 induces p53-dependent apoptosis of SGC7901 gastric cancer cells. | 2008 Apr |
3 |
| 15 |
17286201 | PI 3-K signaling pathway suppresses PMA-induced expression of p21WAF1/Cip1 in human leukemia cells. | 2007 Aug |
1 |
| 16 |
17534123 | Resveratrol-induced apoptosis is associated with activation of p53 and inhibition of protein translation in T47D human breast cancer cells. | 2007 |
1 |
| 17 |
16378598 | Inhibition of the PI3 kinase/Akt pathway enhances doxorubicin-induced apoptotic cell death in tumor cells in a p53-dependent manner. | 2006 Feb 10 |
1 |
| 18 |
16773206 | LY294002, an inhibitor of PI-3K, enhances heat sensitivity independently of p53 status in human lung cancer cells. | 2006 Jul |
3 |
| 19 |
15933740 | The PI3K inhibitor LY294002 prevents p53 induction by DNA damage and attenuates chemotherapy-induced apoptosis. | 2005 Dec |
3 |
| 20 |
15942663 | GSK-3beta reactivation with LY294002 sensitizes hepatoma cells to chemotherapy-induced apoptosis. | 2005 Jul |
1 |
| 21 |
16007163 | Activated AKT regulates NF-kappaB activation, p53 inhibition and cell survival in HTLV-1-transformed cells. | 2005 Oct 6 |
4 |
| 22 |
16024610 | Nitric oxide-induced apoptosis in lymphoblastoid and fibroblast cells dependent on the phosphorylation and activation of p53. | 2005 Jul 15 |
1 |
| 23 |
15363324 | [Overexpression of HER2/neu downregulates wild p53 protein expression via PI3K and Ras/Raf/MEK/ERK pathways in human breast cancer cells]. | 2004 Aug |
2 |
| 24 |
15625017 | Downregulation of wild-type p53 protein by HER-2/neu mediated PI3K pathway activation in human breast cancer cells: its effect on cell proliferation and implication for therapy. | 2004 Dec |
1 |
| 25 |
15634518 | [The effect of HER2/neu overexpression on p53 gene expression, cell proliferation and sensitivity to gamma-irradiation via the PI3K/Akt pathway in breast cancer cell MCF7]. | 2004 Oct |
1 |
| 26 |
12839945 | PTEN and phosphatidylinositol 3'-kinase inhibitors up-regulate p53 and block tumor-induced angiogenesis: evidence for an effect on the tumor and endothelial compartment. | 2003 Jul 1 |
1 |
| 27 |
11923280 | Akt enhances Mdm2-mediated ubiquitination and degradation of p53. | 2002 Jun 14 |
1 |
| 28 |
10771089 | Phosphatidylinositol 3-kinase inhibitors, Wortmannin or LY294002, inhibited accumulation of p21 protein after gamma-irradiation by stabilization of the protein. | 2000 Apr 17 |
1 |