43 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 33562817 | Neurotoxic Effect of Flavonol Myricetin in the Presence of Excess Copper. | 2021 Feb 5 | 1 |
2 | 33875094 | Effects of Copper Nanoparticles on mRNA and Small RNA Expression in Human Hepatocellular Carcinoma (HepG2) Cells. | 2021 Oct 1 | 2 |
3 | 34708319 | High-dose copper activates p53-independent apoptosis through the induction of nucleolar stress in human cell lines. | 2021 Dec | 2 |
4 | 31935835 | Disulfiram/Copper Induces Antitumor Activity against Both Nasopharyngeal Cancer Cells and Cancer-Associated Fibroblasts through ROS/MAPK and Ferroptosis Pathways. | 2020 Jan 6 | 1 |
5 | 32733640 | PI3K/Akt and ERK1/2 Signalling Are Involved in Quercetin-Mediated Neuroprotection against Copper-Induced Injury. | 2020 | 1 |
6 | 33036164 | Identifying Differentially Expressed MicroRNAs, Target Genes, and Key Pathways Deregulated in Patients with Liver Diseases. | 2020 Oct 6 | 1 |
7 | 33327383 | Toward Cancer Diagnostics of the Tumor Suppressor p53 by Surface Enhanced Raman Spectroscopy. | 2020 Dec 14 | 1 |
8 | 33409152 | Disulfiram Chelated With Copper Inhibits the Growth of Gastric Cancer Cells by Modulating Stress Response and Wnt/β-catenin Signaling. | 2020 | 1 |
9 | 31096598 | Neurotoxic Effect of Ethanolic Extract of Propolis in the Presence of Copper Ions is Mediated through Enhanced Production of ROS and Stimulation of caspase-3/7 Activity. | 2019 May 15 | 1 |
10 | 31652494 | The Mechanisms Underlying the Cytotoxic Effects of Copper Via Differentiated Embryonic Chondrocyte Gene 1. | 2019 Oct 22 | 2 |
11 | 31744518 | TPP-related mitochondrial targeting copper (II) complex induces p53-dependent apoptosis in hepatoma cells through ROS-mediated activation of Drp1. | 2019 Nov 19 | 1 |
12 | 31998813 | Novel Isatin-based activator of p53 transcriptional functions in tumor cells. | 2019 Sep | 1 |
13 | 30241011 | Designing anticancer copper(II) complexes by optimizing 2-pyridine-thiosemicarbazone ligands. | 2018 Oct 5 | 1 |
14 | 27913286 | Cytotoxic activity of soy phytoestrogen coumestrol against human breast cancer MCF-7 cells: Insights into the molecular mechanism. | 2017 Jan | 1 |
15 | 26427013 | Ternary Dinuclear Copper(II) Complexes of a Reduced Schiff Base Ligand with Diimine Coligands: DNA Binding, Cytotoxic Cell Apoptosis, and Apoptotic Mechanism. | 2016 Mar | 1 |
16 | 27046389 | Copper induced apoptosis in Caco-2 and Hep-G2 cells: Expression of caspases 3, 8 and 9, AIF and p53. | 2016 Jul-Aug | 1 |
17 | 24975171 | Copper mediated neurological disorder: visions into amyotrophic lateral sclerosis, Alzheimer and Menkes disease. | 2015 Jan | 1 |
18 | 25660211 | DNA damage and induction of apoptosis in pancreatic cancer cells by a new dinuclear bis(triazacyclonane) copper complex. | 2015 Apr | 1 |
19 | 26438057 | Core domain mutant Y220C of p53 protein has a key role in copper homeostasis in case of free fatty acids overload. | 2015 Dec | 5 |
20 | 24445997 | Roles of Atox1 and p53 in the trafficking of copper-64 to tumor cell nuclei: implications for cancer therapy. | 2014 Mar | 2 |
21 | 25216733 | Effects of copper overload in P19 neurons: impairment of glutathione redox homeostasis and crosstalk between caspase and calpain protease systems in ROS-induced apoptosis. | 2014 Dec | 1 |
22 | 23354308 | Degradation of NF-κB, p53 and other regulatory redox-sensitive proteins by thiol-conjugating and -nitrosylating drugs in human tumor cells. | 2013 May | 2 |
23 | 23401182 | The effect of zinc and the role of p53 in copper-induced cellular stress responses. | 2013 Jul | 6 |
24 | 22056254 | Evaluation of copper-64-labeled somatostatin agonists and antagonist in SSTr2-transfected cell lines that are positive and negative for p53: implications for cancer therapy. | 2012 Feb | 5 |
25 | 20875833 | Role of hepatocyte nuclear factor 4α in controlling copper-responsive transcription. | 2011 Jan | 3 |
26 | 20185936 | Penicillamine as a potent protector against injurious effects of cigarette smoke in aerodigestive tract cancer. | 2010 | 1 |
27 | 17938576 | The role of p53 in the trafficking of copper-64 to tumor cell nuclei. | 2008 Jan | 3 |
28 | 18045546 | Neurotoxicity from glutathione depletion is mediated by Cu-dependent p53 activation. | 2008 Jan 1 | 3 |
29 | 18791921 | Association between copper excess, zinc deficiency, and TP53 mutations in esophageal squamous cell carcinoma from Kashmir Valley, India--a high risk area. | 2008 | 1 |
30 | 19013355 | Metals and apoptosis: recent developments. | 2008 | 1 |
31 | 21423838 | Copper-Induced Cytotoxicity and Transcriptional Activation of Stress Genes in Human Liver Carcinoma (HepG(2)) Cells. | 2008 | 1 |
32 | 17234160 | Differences in the cellular response and signaling pathways of cisplatin and BBR3464 ([[trans-PtCl(NH3)(2)]2mu-(trans-Pt(NH3)(2)(H2N(CH2)(6)-NH2)2)]4+) influenced by copper homeostasis. | 2007 May 1 | 1 |
33 | 17477370 | P53 mediated regulation of metallothionein transcription in breast cancer cells. | 2007 Dec 15 | 1 |
34 | 15711927 | Role of p53 and reactive oxygen species in apoptotic response to copper and zinc in epithelial breast cancer cells. | 2005 Jan | 6 |
35 | 15880691 | Inhibition of extracellular signal regulated kinase (ERK) leads to apoptosis inducing factor (AIF) mediated apoptosis in epithelial breast cancer cells: the lack of effect of ERK in p53 mediated copper induced apoptosis. | 2005 Aug 15 | 1 |
36 | 16246896 | Copper alters the conformation and transcriptional activity of the tumor suppressor protein p53 in human Hep G2 cells. | 2005 Nov | 5 |
37 | 16391388 | Expression profiling of p53-target genes in copper-mediated neuronal apoptosis. | 2005 | 5 |
38 | 15001399 | Differential regulation of signal transduction pathways in wild type and mutated p53 breast cancer epithelial cells by copper and zinc. | 2004 Mar 15 | 4 |
39 | 11964141 | Copper uptake is required for pyrrolidine dithiocarbamate-mediated oxidation and protein level increase of p53 in cells. | 2002 Aug 1 | 3 |
40 | 12095159 | Zinc inhibits the nuclear translocation of the tumor suppressor protein p53 and protects cultured human neurons from copper-induced neurotoxicity. | 2002 | 12 |
41 | 11340094 | Tumor suppressor protein p53 mRNA and subcellular localization are altered by changes in cellular copper in human Hep G2 cells. | 2001 May | 5 |
42 | 11050162 | Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases. | 2000 Nov 7 | 1 |
43 | 9315628 | Regulation of p53 by metal ions and by antioxidants: dithiocarbamate down-regulates p53 DNA-binding activity by increasing the intracellular level of copper. | 1997 Oct | 5 |