Cyclic AMP

tumor protein p53 ; Homo sapiens







52 Article(s)
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1 34880123 cAMP-Mediated Autophagy Promotes Cell Survival via ROS-Induced Activation of PARP1: Implications for Treatment of Acute Lymphoblastic Leukemia. 2022 Mar 1 1
2 35517499 The Apoptotic Resistance of BRCA1-Deficient Ovarian Cancer Cells is Mediated by cAMP. 2022 1
3 32098292 Germline Variants in Phosphodiesterase Genes and Genetic Predisposition to Pediatric Adrenocortical Tumors. 2020 Feb 22 1
4 29233839 Genetics of tumors of the adrenal cortex. 2018 Mar 1
5 29329830 Theoretical research in structure characteristics of different inhibitors and differences of binding modes with CBP bromodomain. 2018 Feb 1 1
6 30100998 cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53. 2018 Jul 13 4
7 30154459 Tolerance to sustained activation of the cAMP/Creb pathway activity in osteoblastic cells is enabled by loss of p53. 2018 Aug 28 6
8 29131834 Plasma microRNA profiling: Exploring better biomarkers for lymphoma surveillance. 2017 1
9 26976603 Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein. 2016 Mar 29 3
10 27383270 Inactivation of oncogenic cAMP-specific phosphodiesterase 4D by miR-139-5p in response to p53 activation. 2016 Jul 7 1
11 28357198 Cyclic AMP-Induced p53 Destabilization is Independent of CREB in Pre-B Acute Lymphoblastic Leukemia Cells. 2016 Fall 3
12 25524737 PI3K/AKT and Mdm2 activation are associated with inhibitory effect of cAMP increasing agents on DNA damage-induced cell death in human pre-B NALM-6 cells. 2015 Jan 15 2
13 25623255 Bone marrow stroma-derived PGE2 protects BCP-ALL cells from DNA damage-induced p53 accumulation and cell death. 2015 Jan 27 3
14 26261798 Elevation of cAMP Levels Inhibits Doxorubicin-Induced Apoptosis in Pre- B ALL NALM- 6 Cells Through Induction of BAD Phosphorylation and Inhibition of P53 Accumulation. 2015 Spring 4
15 23299313 Selective inhibition of cell death in malignant vs normal B-cell precursors: implications for cAMP in development and treatment of BCP-ALL. 2013 Mar 7 2
16 23316052 Dual-site interactions of p53 protein transactivation domain with anti-apoptotic Bcl-2 family proteins reveal a highly convergent mechanism of divergent p53 pathways. 2013 Mar 8 1
17 23483263 cAMP signalling inhibits p53 acetylation and apoptosis via HDAC and SIRT deacetylases. 2013 May 15
18 23555731 Global conformational selection and local induced fit for the recognition between intrinsic disordered p53 and CBP. 2013 1
19 24002658 Role of p53 in cAMP/PKA pathway mediated apoptosis. 2013 Dec 1
20 21510868 Hyperactivation of NF-κB via the MEK signaling is indispensable for the inhibitory effect of cAMP on DNA damage-induced cell death. 2011 Apr 21 2
21 21619452 Cyclic AMP-induced p53 destabilization is independent of EPAC in pre-B acute lymphoblastic leukemia cells in vitro. 2011 Jun 7
22 21655990 Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial. 2011 Aug 1
23 21750659 Activation of cAMP signaling interferes with stress-induced p53 accumulation in ALL-derived cells by promoting the interaction between p53 and HDM2. 2011 Jul 9
24 19882354 Inhibitory role of cAMP on doxorubicin-induced apoptosis in pre-B ALL cells through dephosphorylation of p53 serine residues. 2010 Feb 4
25 20199942 mot-2-Mediated cross talk between nuclear factor-B and p53 is involved in arsenite-induced tumorigenesis of human embryo lung fibroblast cells. 2010 Jul 3
26 20624391 Elevation of cyclic AMP causes an imbalance between NF-kappaB and p53 in NALM-6 cells treated by doxorubicin. 2010 Aug 4 2
27 18310282 Enhanced expression of aromatase in p53-inactivated mammary epithelial cells. 2008 Mar 1
28 18409049 Differential regulation of ErbB2 expression by cAMP-dependent protein kinase in tamoxifen-resistant breast cancer cells. 2008 Mar 1
29 19026785 Inhibition of PAX3 by TGF-beta modulates melanocyte viability. 2008 Nov 21 1
30 17130833 Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion. 2007 May 17 1
31 16837854 K+ regulates DNA binding of transcription factors to control gene expression related to neuronal apoptosis. 2006 Jul 31 1
32 15806165 Role of the adenosine 3',5'-cyclic monophosphate (cAMP) in enhancing the efficacy of siRNA-mediated gene silencing in neuroblastoma cells. 2005 Jun 9 1
33 16275167 A scientific rationale for the CREST trial results: evidence for the mechanism of action of cilostazol in restenosis. 2005 Dec 15 1
34 15154850 The CBP/p300 TAZ1 domain in its native state is not a binding partner of MDM2. 2004 Aug 1 1
35 15472230 Wild-type p53 protein is up-regulated upon cyclic adenosine monophosphate-induced differentiation of human endometrial stromal cells. 2004 Oct 3
36 12501250 Human immunodeficiency virus type-1 Tat/co-activator acetyltransferase interactions inhibit p53Lys-320 acetylation and p53-responsive transcription. 2003 Apr 4 1
37 11076933 p300 does not require its acetylase activity to stimulate p73 function. 2001 Jan 5 1
38 11196199 Human homologue of yeast Rad23 protein A interacts with p300/cyclic AMP-responsive element binding (CREB)-binding protein to down-regulate transcriptional activity of p53. 2001 Jan 1 1
39 11428715 cAMP-induced apoptosis in granulosa cells is associated with up-regulation of P53 and bax and down-regulation of clusterin. 2001 Feb-May 3
40 11709055 UV stimulation induces nuclear factor kappaB (NF-kappaB) DNA-binding activity but not transcriptional activation. 2001 Nov 1
41 10642304 Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells, accompanied by induction of p53 and p21. 2000 Jan 5
42 10848610 p53 recruitment of CREB binding protein mediated through phosphorylated CREB: a novel pathway of tumor suppressor regulation. 2000 Jul 2
43 9651310 Differential regulation of p53-dependent and -independent proliferating cell nuclear antigen gene transcription by 12 S E1A oncoprotein requires CBP. 1998 Jul 10 1
44 9661907 p53 genes mutated in the DNA binding site or at a specific COOH-terminal site exert divergent effects on thyroid cell growth and differentiation. 1998 Jul 1 4
45 9690520 Etoposide and cisplatin induced apoptosis in activated RAW 264.7 macrophages is attenuated by cAMP-induced gene expression. 1998 Jul 23 3
46 9766444 p53-dependent and -independent differentiation of leukemic U-937 cells: relationship to cell cycle control. 1998 Oct 3
47 9774464 Oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system. 1998 Oct 23 1
48 9794481 Modulation of Mdm2 expression and p53-induced apoptosis in immortalized human ovarian granulosa cells. 1998 Nov 2
49 8733010 Cross-talk between cAMP and p53-generated signals in induction of differentiation and apoptosis in steroidogenic granulosa cells. 1996 Apr 3
50 7737366 Involvement of p53 expression in cAMP-mediated apoptosis in immortalized granulosa cells. 1995 May 3