Pub. Date : 2013 Mar 8
PMID : 23316052
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Taken together with the mutagenesis, isothermal titration calorimetry, and paramagnetic relaxation enhancement data, our structural comparisons provided the structural basis of p53TAD2-mediated interaction with the anti-apoptotic proteins, revealing that Bcl-X(L)/Bcl-2, MDM2, and cAMP-response element-binding protein-binding protein/p300 share highly similar modes of binding to the dual p53TAD motifs, p53TAD1 and p53TAD2. | Cyclic AMP | tumor protein p53 | Homo sapiens |