Carboplatin

tumor protein p53 ; Homo sapiens







42 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35190375 Clinical efficacy of atezolizumab plus bevacizumab and chemotherapy in KRAS-mutated non-small cell lung cancer with STK11, KEAP1, or TP53 comutations: subgroup results from the phase III IMpower150 trial. 2022 Feb 1
2 33002289 Gallic acid potentiates the apoptotic effect of paclitaxel and carboplatin via overexpression of Bax and P53 on the MCF-7 human breast cancer cell line. 2021 Feb 1
3 34732786 The chemotherapeutic drug carboplatin affects macrophage responses to LPS and LPS tolerance via epigenetic modifications. 2021 Nov 3 1
4 31119730 Prevalence and clinical impact of TP53 germline mutations in Chinese women with breast cancer. 2020 Jan 15 3
5 31886905 Mode of action of carboplatin via activating p53/miR-145 axis in head and neck cancers. 2020 Dec 5
6 31937750 Long Non-Coding RNA (lncRNA) BMP/OP-Responsive Gene (BORG) Promotes Development of Chemoresistance of Colorectal Cancer Cells to Carboplatin. 2020 Jan 15 1
7 32072678 The combination of artesunate and carboplatin exerts a synergistic anti-tumour effect on non-small cell lung cancer. 2020 Jun 1
8 31322224 Inhibition of MCM2 enhances the sensitivity of ovarian cancer cell to carboplatin. 2019 Sep 2
9 31621389 Overexpression of Long Noncoding RNA E2F-Mediated Cell Proliferation Enhancing Long Noncoding RNA Is Involved in the Development of Chemoresistance of Cancer Cells to Carboplatin in Ovarian Endometrioid Adenocarcinoma. 2019 Nov 1
10 29854627 Neuro- and nephroprotective effect of grape seed proanthocyanidin extract against carboplatin and thalidomide through modulation of inflammation, tumor suppressor protein p53, neurotransmitters, oxidative stress and histology. 2018 2
11 27611952 Role of TP53 mutations in triple negative and HER2-positive breast cancer treated with neoadjuvant anthracycline/taxane-based chemotherapy. 2016 Oct 18 1
12 27998224 Phase II Study of WEE1 Inhibitor AZD1775 Plus Carboplatin in Patients With TP53-Mutated Ovarian Cancer Refractory or Resistant to First-Line Therapy Within 3 Months. 2016 Dec 20 1
13 25490861 Knockdown of platinum-induced growth differentiation factor 15 abrogates p27-mediated tumor growth delay in the chemoresistant ovarian cancer model A2780cis. 2015 Feb 1
14 25658463 WIP1 phosphatase as a potential therapeutic target in neuroblastoma. 2015 1
15 26722257 Expression of mutant p53 in oral squamous cell carcinoma is correlated with the effectiveness of intra-arterial chemotherapy. 2015 Nov 1
16 24333234 Utilization of an ex vivo human placental perfusion model to predict potential fetal exposure to carboplatin during pregnancy. 2014 Mar 1
17 25426548 Targeting of mutant p53-induced FoxM1 with thiostrepton induces cytotoxicity and enhances carboplatin sensitivity in cancer cells. 2014 Nov 30 1
18 24601052 In vitro chemosensitivity assay of ascites in epithelial ovarian cancer. 2013 1
19 22763759 Loss of TP53 expression in immortalized choroid plexus epithelial cells results in increased resistance to anticancer agents. 2012 Sep 1
20 21868512 The mTOR inhibitor RAD001 sensitizes tumor cells to the cytotoxic effect of carboplatin in breast cancer in vitro. 2011 Sep 5
21 20096282 Akt inhibitor enhances apoptotic effect of carboplatin on human epithelial ovarian carcinoma cell lines. 2010 Apr 25 1
22 20180806 Hyperthermia-associated carboplatin resistance: differential role of p53, HSF1 and Hsp70 in hepatoma cells. 2010 May 1
23 19887545 Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents. 2009 Nov 1
24 18690840 FHIT and p53 status and response to platinum-based treatment in advanced non-small cell lung cancer. 2008 Aug 1
25 17063488 Gadd45alpha does not modulate the carboplatin or 5-fluorouracil-induced apoptosis in human papillomavirus-positive cells. 2007 Apr 1 1
26 17146434 Mouse double minute antagonist Nutlin-3a enhances chemotherapy-induced apoptosis in cancer cells with mutant p53 by activating E2F1. 2007 May 24 1
27 17208232 p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: a novel target of p53 in apoptosis. 2007 Jan 23 7
28 16459017 Prognostic significance of p53 mutation in suboptimally resected advanced ovarian carcinoma treated with the combination chemotherapy of paclitaxel and carboplatin. 2006 Sep 28 1
29 15854392 [Relationship between the acquired multi-drug resistance of human large cell lung cancer cell line NCI-H460 by cisplatin selection and p53 mutation]. 2005 Feb 1
30 15908516 Chemotherapy compounds in cervical cancer cells primed by reconstitution of p53 function after short interfering RNA-mediated degradation of human papillomavirus 18 E6 mRNA: opposite effect of siRNA in combination with different drugs. 2005 Aug 1
31 16200870 [Correlation between p53 gene mutation and the expression of tumor drug resistance genes in lung cancer and its clinical significance]. 2004 Oct 1
32 12684687 The effect of loss of Brca1 on the sensitivity to anticancer agents in p53-deficient cells. 2003 May 1
33 11862428 Drug resistance in malignant rhabdoid tumor cell lines. 2002 Feb 1
34 12168940 Correlation of clinical outcome with p53 and p21 status in patients with advanced transitional-cell carcinoma treated with paclitaxel and carboplatin. 2002 Mar-Apr 2
35 12499281 Chemoradiation of cervical cancer cells: targeting human papillomavirus E6 and p53 leads to either augmented or attenuated apoptosis depending on the platinum carrier ligand. 2002 Dec 15 3
36 11507071 Loss of p53 function confers high-level multidrug resistance in neuroblastoma cell lines. 2001 Aug 15 1
37 11595686 Correlation of p53 mutations with resistance to platinum-based chemotherapy and shortened survival in ovarian cancer. 2001 Oct 3
38 10190788 Carboplatin and paclitaxel, alone and in combination: dose escalation, measurement of renal function, and role of the p53 tumor suppressor gene. 1999 Feb 2
39 9664115 The apoptotic effects of cisplatin and carboplatin in retinoblastoma Y79 cells. 1998 Aug 1
40 10328543 Accumulation of class I mutant p53 and apoptosis induced by carboplatin in a human glioma cell line. 1998 1
41 9061063 Early results of the value of p53 in predicting survival in a homogeneous cohort of patients with invasive bladder cancer treated with a neoadjuvant carboplatin-based regimen (M-CAVI). 1996 Nov-Dec 1
42 9081399 Ovarian cancer, from the laboratory to the clinic: challenges for the future. 1996 Jan 1