Pub. Date : 2007 Jan 23
PMID : 17208232
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: a novel target of p53 in apoptosis. | Carboplatin | tumor protein p53 | Homo sapiens |
| 2 | p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: a novel target of p53 in apoptosis. | Carboplatin | tumor protein p53 | Homo sapiens |
| 3 | Under similar treatment conditions p53 was also involved in Carb induced apoptosis in these cells. | Carboplatin | tumor protein p53 | Homo sapiens |
| 4 | Therefore, we investigated the relation between p53 and ERK in Carb induced apoptosis in these cells. | Carboplatin | tumor protein p53 | Homo sapiens |
| 5 | Abrogation of p53 transactivation activity by pifithrin alpha or dominant-negative mutant of p53 resulted in decrease in activation of ERK in Carb treated cells. | Carboplatin | tumor protein p53 | Homo sapiens |
| 6 | Abrogation of p53 transactivation activity by pifithrin alpha or dominant-negative mutant of p53 resulted in decrease in activation of ERK in Carb treated cells. | Carboplatin | tumor protein p53 | Homo sapiens |
| 7 | The present study for the first time proposes that p53 may act as one of the upstream regulators of ERK activation for the induction of apoptosis in Carb treated cervical cancer cells. | Carboplatin | tumor protein p53 | Homo sapiens |