Title : Inhibition of MCM2 enhances the sensitivity of ovarian cancer cell to carboplatin.

Pub. Date : 2019 Sep

PMID : 31322224






2 Functional Relationships(s)
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1 Furthermore, knockdown of MCM2 together with carboplatin treatment or UV irradiation increased the protein expression level of gamma-H2A histone family member X and p53 compared with control cells. Carboplatin tumor protein p53 Homo sapiens
2 The present data suggested that the increased sensitivity to carboplatin may occur via the p53-dependent apoptotic response. Carboplatin tumor protein p53 Homo sapiens