Tetradecanoylphorbol Acetate

tumor protein p53 ; Homo sapiens







50 Article(s)
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Pub. Year
#Total Relationships
1 33791017 Bioinformatics analysis of biomarkers of aristolochic acid-induced early nephrotoxicity in embryonic stem cells. 2021 May 1
2 32705219 MDM2 as a target for ellagic acid‑mediated suppression of prostate cancer cells in vitro. 2020 Sep 2
3 31726940 Mutant p53 drives cancer chemotherapy resistance due to loss of function on activating transcription of PUMA. 2019 Dec 6
4 29660338 Different molecular mechanisms of HTLV-1 and HIV LTR activation by TPA. 2018 Jun 7 8
5 28765903 Wild-type p53 controls the level of fibronectin expression in breast cancer cells. 2017 Oct 4
6 26581877 Transient delay of radiation-induced apoptosis by phorbol acetate. 2016 Mar 1
7 27409664 The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer. 2016 Aug 2 1
8 26231140 Effect of tannic acid, resveratrol and its derivatives, on oxidative damage and apoptosis in human neutrophils. 2015 Oct 2
9 26431317 Synergistic Gene Expression Signature Observed in TK6 Cells upon Co-Exposure to UVC-Irradiation and Protein Kinase C-Activating Tumor Promoters. 2015 1
10 24960060 Protein kinase C-activating tumor promoters modulate the DNA damage response in UVC-irradiated TK6 cells. 2014 Aug 17 1
11 22020547 TPA-induced p21 expression augments G2/M arrest through a p53-independent mechanism in human breast cancer cells. 2012 Feb 8
12 22299029 Differential role of PKC-induced c-Jun in HTLV-1 LTR activation by 12-O-tetradecanoylphorbol-13-acetate in different human T-cell lines. 2012 1
13 22911849 p53 acts as a co-repressor to regulate keratin 14 expression during epidermal cell differentiation. 2012 4
14 21705328 Dual function of protein kinase C (PKC) in 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced manganese superoxide dismutase (MnSOD) expression: activation of CREB and FOXO3a by PKC-alpha phosphorylation and by PKC-mediated inactivation of Akt, respectively. 2011 Aug 26 1
15 22009531 Manganese superoxide dismutase is a p53-regulated gene that switches cancers between early and advanced stages. 2011 Nov 1 2
16 20976134 Mitochondrial uncoupling inhibits p53 mitochondrial translocation in TPA-challenged skin epidermal JB6 cells. 2010 Oct 18 5
17 19366707 Nucleophosmin blocks mitochondrial localization of p53 and apoptosis. 2009 Jun 12 2
18 19541923 p53 inhibition of AP1-dependent TFF2 expression induces apoptosis and inhibits cell migration in gastric cancer cells. 2009 Aug 2
19 18358838 Blocking mitochondrial permeability transition prevents p53 mitochondrial translocation during skin tumor promotion. 2008 Apr 16 1
20 18397889 Tumor suppressor protein p53 regulates megakaryocytic polyploidization and apoptosis. 2008 Jun 6 1
21 16267831 Mutant human tumor suppressor p53 modulates the activation of mitogen-activated protein kinase and nuclear factor-kappaB, but not c-Jun N-terminal kinase and activated protein-1. 2006 Jan 8
22 16740634 Specificity protein 1-dependent p53-mediated suppression of human manganese superoxide dismutase gene expression. 2006 Aug 4 1
23 17108111 Mutant p53 protects cells from 12-O-tetradecanoylphorbol-13-acetate-induced death by attenuating activating transcription factor 3 induction. 2006 Nov 15 5
24 15770664 Fast apoptosis and erythroid differentiation induced by imatinib mesylate in JURL-MK1 cells. 2005 May 15 2
25 15867370 p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase. 2005 May 1 5
26 15899818 Matrix metalloproteinases 9 and 10 inhibit protein kinase C-potentiated, p53-mediated apoptosis. 2005 May 15 1
27 14584049 Resistance to UV-induced apoptosis in human keratinocytes during accelerated senescence is associated with functional inactivation of p53. 2004 Jan 3
28 14699137 Inhibition of human p53 basal transcription by down-regulation of protein kinase Cdelta. 2004 Mar 12 1
29 15138488 JNK interacting protein 1 (JIP-1) protects LNCaP prostate cancer cells from growth arrest and apoptosis mediated by 12-0-tetradecanoylphorbol-13-acetate (TPA). 2004 May 17 1
30 12917633 Role of protein kinase C and the Sp1-p53 complex in activation of p21(WAF-1) expression by 12-O-tetradecanoylphorbol-13-acetate in human T cells. 2003 Aug 14 1
31 11222091 Sp1-p53 heterocomplex mediates activation of HTLV-I long terminal repeat by 12-O-tetradecanoylphorbol-13-acetate that is antagonized by protein kinase C. 2001 Mar 1 4
32 10529369 p53 down-regulates ER-responsive genes by interfering with the binding of ER to ERE. 1999 Oct 22 1
33 10543370 Contributions of p53 and PMA to gamma-irradiation induced apoptosis in Jurkat cells. 1999 Aug 2
34 10547071 The expression of p53 tumor suppressor gene in breast cancer cells is down-regulated by cytokine oncostatin M. 1999 Oct 1
35 10601254 The role of the Smad3 protein in phorbol ester-induced promoter expression. 1999 Dec 24 2
36 9620358 Differential expression of p53 tumor suppressor protein and IL-2 in activated T cells from elderly humans. 1998 May 2
37 9879997 Induction of apoptosis in breast cancer cells by TPA. 1998 Dec 3 2
38 9000576 Defects in p21WAF1/CIP1, Rb, and c-myc signaling in phorbol ester-resistant cancer cells. 1997 Jan 15 2
39 9467850 Genetic changes associated with immortalization. A review. 1997 Nov 2
40 8603737 Activation of SRC family kinases in human neutrophils. Evidence that p58C-FGR and p53/56LYN redistributed to a Triton X-100-insoluble cytoskeletal fraction, also enriched in the caveolar protein caveolin, display an enhanced kinase activity. 1996 Feb 12 3
41 8622872 Regulation of p21WAF1/CIP1 expression by p53-independent pathways. 1996 Apr 4 2
42 8927716 Effects of 60-Hz fields, estradiol and xenoestrogens on human breast cancer cells. 1996 Oct 2
43 21541584 p53 expression and tumor proliferative activity in testicular germ-cell tumors. 1996 Oct 2
44 7560079 Phorbol esters induce death in MCF-7 breast cancer cells with altered expression of protein kinase C isoforms. Role for p53-independent induction of gadd-45 in initiating death. 1995 Oct 1
45 7727777 Anti-IgM induces transforming growth factor-beta sensitivity in a human B-lymphoma cell line: inhibition of growth is associated with a downregulation of mutant p53. 1995 May 1 2
46 7834638 p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation. 1995 Feb 1 1
47 8018565 Tumor-promoting phorbol ester transiently down-modulates the p53 level and blocks the cell cycle. 1994 Mar 3
48 8108142 Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression. 1994 Mar 2
49 8352891 No point mutation of Ha-ras or p53 genes expressed in preneoplastic-to-neoplastic progression as modeled in mouse JB6 cell variants. 1993 4
50 1868448 Levels of p53 protein increase with maturation in human hematopoietic cells. 1991 Aug 15 1