Title : Blocking mitochondrial permeability transition prevents p53 mitochondrial translocation during skin tumor promotion.

Pub. Date : 2008 Apr 16

PMID : 18358838






1 Functional Relationships(s)
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1 Our results demonstrated that CsA and BA blocked TPA-induced p53 translocation, leading to protection against the loss of mitochondrial membrane potential and Complex I activity, and eventually suppression of apoptosis. Tetradecanoylphorbol Acetate tumor protein p53 Homo sapiens