Pub. Date : 2005 May 1
PMID : 15867370
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Herein, we show that p53 translocation to mitochondria precedes its translocation to nucleus in JB6 skin epidermal cells treated with the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). | Tetradecanoylphorbol Acetate | tumor protein p53 | Homo sapiens |
2 | Herein, we show that p53 translocation to mitochondria precedes its translocation to nucleus in JB6 skin epidermal cells treated with the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). | Tetradecanoylphorbol Acetate | tumor protein p53 | Homo sapiens |
3 | Translocation of p53 to mitochondria occurs within 10 minutes after TPA application. | Tetradecanoylphorbol Acetate | tumor protein p53 | Homo sapiens |
4 | In contrast to the immediate action on mitochondria, p53 transcriptional activity in the nucleus increases at 1 hour following TPA application, accompanied by an increase in the levels of its target gene bax at 15 hours following TPA treatment. | Tetradecanoylphorbol Acetate | tumor protein p53 | Homo sapiens |
5 | In contrast to the immediate action on mitochondria, p53 transcriptional activity in the nucleus increases at 1 hour following TPA application, accompanied by an increase in the levels of its target gene bax at 15 hours following TPA treatment. | Tetradecanoylphorbol Acetate | tumor protein p53 | Homo sapiens |