Quercetin

tumor protein p53 ; Homo sapiens







85 Article(s)
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51 22765290 Plant natural compounds: targeting pathways of autophagy as anti-cancer therapeutic agents. 2012 Oct 1
52 21196432 Exploiting tyrosinase expression and activity in melanocytic tumors: quercetin and the central role of p53. 2011 Dec 2
53 21479885 Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation. 2011 Dec 1
54 21965740 Phytoestrogens induce apoptosis via extrinsic pathway, inhibiting nuclear factor-kappaB signaling in HER2-overexpressing breast cancer cells. 2011 Oct 1
55 21994207 Enhancement of carboplatin- and quercetin-induced cell death by roscovitine is Akt dependent and p53 independent in hepatoma cells. 2011 Dec 1
56 22070678 Quercetin as a systemic chemopreventative agent: structural and functional mechanisms. 2011 Dec 1
57 20540768 Quercetin abrogates chemoresistance in melanoma cells by modulating deltaNp73. 2010 Jun 11 1
58 20681654 Apoptotic effect of quercetin on HT-29 colon cancer cells via the AMPK signaling pathway. 2010 Aug 11 4
59 20803121 Quercetin-mediated cell cycle arrest and apoptosis involving activation of a caspase cascade through the mitochondrial pathway in human breast cancer MCF-7 cells. 2010 Aug 1
60 20858478 The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-κB inhibition. 2010 Dec 15 2
61 19424582 Isolation of a chemical inhibitor against K-Ras-induced p53 suppression through natural compound screening. 2009 Jun 3
62 19623560 Regulation of survivin and Bcl-2 in HepG2 cell apoptosis induced by quercetin. 2009 Jul 1
63 18323654 Stabilization of p53 is involved in quercetin-induced cell cycle arrest and apoptosis in HepG2 cells. 2008 Mar 11
64 18608579 p53 status-dependent sensitization of human tumour cells to hyperthermia by plant flavonol. 2008 Aug 1
65 18791269 Tyrosinase overexpression promotes ATM-dependent p53 phosphorylation by quercetin and sensitizes melanoma cells to dacarbazine. 2008 1
66 18813348 Hsf1 is required for the nuclear translocation of p53 tumor suppressor. 2008 Oct 1
67 17191121 NAG-1 up-regulation mediated by EGR-1 and p53 is critical for quercetin-induced apoptosis in HCT116 colon carcinoma cells. 2007 Feb 2
68 17520098 Quercetin induces cell cycle G1 arrest through elevating Cdk inhibitors p21 and p27 in human hepatoma cell line (HepG2). 2007 Apr 2
69 18001220 Quercetin selectively inhibits bioreduction and enhances apoptosis in melanoma cells that overexpress tyrosinase. 2007 1
70 16720314 Growth inhibitory effects of quercetin on bladder cancer cell. 2006 Sep 1 2
71 16898267 Quercetin induces p53-independent apoptosis in human prostate cancer cells by modulating Bcl-2-related proteins: a possible mediation by IGFBP-3. 2006 2
72 16948901 [Quercetin inhibits growth and induces apoptosis of human gastric carcinoma cells]. 2006 Sep 1
73 15735102 Ellagic acid potentiates the effect of quercetin on p21waf1/cip1, p53, and MAP-kinases without affecting intracellular generation of reactive oxygen species in vitro. 2005 Mar 4
74 15795422 (-)Epigallocatechin gallate and quercetin enhance survival signaling in response to oxidant-induced human endothelial apoptosis. 2005 Apr 2
75 16211300 Quercetin induces gadd45 expression through a p53-independent pathway. 2005 Nov 3
76 14767529 Quercetin-induced growth inhibition and cell death in nasopharyngeal carcinoma cells are associated with increase in Bad and hypophosphorylated retinoblastoma expressions. 2004 Mar 2
77 15177039 The isoflavonoids genistein and quercetin activate different stress signaling pathways as shown by analysis of site-specific phosphorylation of ATM, p53 and histone H2AX. 2004 Mar 4 2
78 15456784 Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells. 2004 Dec 31 8
79 12589822 Quercetin exerts multiple inhibitory effects on vascular smooth muscle cells: role of ERK1/2, cell-cycle regulation, and matrix metalloproteinase-9. 2003 Feb 21 2
80 11408351 Quercetin, E7 and p53 in papillomavirus oncogenic cell transformation. 2001 Jul 4
81 11562764 Induction of cell cycle arrest and apoptosis in human breast cancer cells by quercetin. 2001 Oct 1
82 10082992 Quercetin inhibited DNA synthesis and induced apoptosis associated with increase in c-fos mRNA level and the upregulation of p21WAF1CIP1 mRNA and protein expression during liver regeneration after partial hepatectomy. 1999 Mar 14 2
83 10408175 Effects of protein kinase inhibitors on the accumulation kinetics of p53 protein in normal human embryo cells following X-irradiation. 1999 Mar 1
84 8895505 Flavonoids activate wild-type p53. 1996 Oct 17 1
85 8162591 Quercetin mediates the down-regulation of mutant p53 in the human breast cancer cell line MDA-MB468. 1994 May 1 4