| 1 |
29133879 | Development of a genetic sensor that eliminates p53 deficient cells. | 2017 Nov 13 |
1 |
| 2 |
26934443 | Exogenous p53 and ASPP2 expression enhances rAdV-TK/ GCV-induced death in hepatocellular carcinoma cells lacking functional p53. | 2016 Apr 5 |
5 |
| 3 |
27464624 | Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces FasL and TNFR2 mediated antitumor apoptosis in solid tumors. | 2016 Jul 27 |
1 |
| 4 |
25217394 | The cell death and DNA damages caused by the Tet-On regulating HSV-tk/GCV suicide gene system in MCF-7 cells. | 2014 Sep |
1 |
| 5 |
21946198 | [DNA damage caused by suicide gene therapy system under Tet-On regulation in breast cancer cells]. | 2011 Sep |
2 |
| 6 |
22174876 | Adenoviral vector driven by a minimal Rad51 promoter is selective for p53-deficient tumor cells. | 2011 |
1 |
| 7 |
20187803 | Selective suicide gene therapy of colon cancer cell lines exploiting fibroblast growth factor 18 promoter. | 2010 Feb |
1 |
| 8 |
20199127 | Selective suicide gene therapy of colon cancer exploiting the urokinase plasminogen activator receptor promoter. | 2010 Apr 1 |
2 |
| 9 |
16838851 | Apoptotic effect of ganciclovir on primary effusion lymphoma cells infected with Kaposi's sarcoma-associated herpesvirus. | 2006 |
2 |
| 10 |
15592511 | Mechanisms of thymidine kinase/ganciclovir and cytosine deaminase/ 5-fluorocytosine suicide gene therapy-induced cell death in glioma cells. | 2005 Feb 10 |
3 |
| 11 |
15804027 | [The effects of HSV-tk suicide gene and wild-type p53 gene on pleomorphic adenoma cells of salivary gland]. | 2005 Feb |
1 |
| 12 |
15916863 | The suppressed proliferation and premature senescence by ganciclovir in p53-mutated human non-small-lung cancer cells acquiring herpes simplex virus-thymidine kinase cDNA. | 2005 |
4 |
| 13 |
16050136 | Influence of p53 status on the HSV-Tk/GCV-induced bystander effect in a panel of human ovarian carcinoma cell lines. | 2005 |
4 |
| 14 |
12869633 | P53-dependent cell-killing by selective repression of thymidine kinase and reduced prodrug activation. | 2003 Aug |
4 |
| 15 |
11871818 | A novel suicide gene therapy system for p53-mutated cells using a wild-type p53-specific promoter and Cre/loxP switch. | 2002 |
1 |
| 16 |
11313826 | Death receptor-independent cytochrome c release and caspase activation mediate thymidine kinase plus ganciclovir-mediated cytotoxicity in LN-18 and LN-229 human malignant glioma cells. | 2001 Mar |
1 |
| 17 |
11526536 | Mechanisms of cell death induced by suicide genes encoding purine nucleoside phosphorylase and thymidine kinase in human hepatocellular carcinoma cells in vitro. | 2001 Sep |
3 |
| 18 |
11559571 | Self-deleting suicide vectors (SDSV): selective killing of p53-deficient cancer cells. | 2001 Sep 15 |
1 |
| 19 |
10866313 | Mitochondrial amplification of death signals determines thymidine kinase/ganciclovir-triggered activation of apoptosis. | 2000 Jun 15 |
3 |
| 20 |
10195885 | Differential chemosensitivity of breast cancer cells to ganciclovir treatment following adenovirus-mediated herpes simplex virus thymidine kinase gene transfer. | 1999 Mar-Apr |
3 |
| 21 |
10411938 | Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases. | 1999 Jul 20 |
2 |
| 22 |
10628368 | Differential efficacy of suicide gene therapy by herpes simplex virus-thymidine kinase gene reflects the status of p53 gene in human esophageal cancer cells. | 1999 Sep-Oct |
1 |
| 23 |
8700554 | Ganciclovir-induced ablation non-proliferating thyrocytes expressing herpesvirus thymidine kinase occurs by p53-independent apoptosis. | 1996 Jul 4 |
2 |