Cytarabine

MCL1 apoptosis regulator, BCL2 family member ; Homo sapiens







12 Article(s)
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1 35443722 Artesunate improves venetoclax plus cytarabine AML cell targeting by regulating the Noxa/Bim/Mcl-1/p-Chk1 axis. 2022 Apr 20 5
2 34707185 CD157 signaling promotes survival of acute myeloid leukemia cells and modulates sensitivity to cytarabine through regulation of anti-apoptotic Mcl-1. 2021 Oct 27 2
3 34718324 A prospective biomarker analysis of alvocidib followed by cytarabine and mitoxantrone in MCL-1-dependent relapsed/refractory acute myeloid leukemia. 2021 Oct 30 1
4 29872325 miR-134 increases the antitumor effects of cytarabine by targeting Mnks in acute myeloid leukemia cells. 2018 1
5 30361682 Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML. 2018 Oct 25 1
6 27103402 Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcome by Combination with Daunorubicin or Cytarabine in AML Cells. 2016 Sep 1 3
7 27462781 Inhibition of Mnk enhances apoptotic activity of cytarabine in acute myeloid leukemia cells. 2016 Aug 30 1
8 23441221 Chemoresistance of human monocyte-derived dendritic cells is regulated by IL-17A. 2013 1
9 22829255 Targeting MCL-1 sensitizes FLT3-ITD-positive leukemias to cytotoxic therapies. 2012 Mar 1
10 21212792 The cyclin-dependent kinase inhibitor SNS-032 has single agent activity in AML cells and is highly synergistic with cytarabine. 2011 Mar 2
11 16818278 The mechanisms of Ara-C-induced apoptosis of resting B-chronic lymphocytic leukemia cells. 2006 Jul 1
12 11830549 An MCL1-overexpressing Burkitt lymphoma subline exhibits enhanced survival on exposure to serum deprivation, topoisomerase inhibitors, or staurosporine but remains sensitive to 1-beta-D-arabinofuranosylcytosine. 2002 Feb 1 1