Title : Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML.

Pub. Date : 2018 Oct 25

PMID : 30361682






1 Functional Relationships(s)
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1 Furthermore, combined inhibition of Bcl-2/Bcl-XL and Mcl-1 could revert BMSC-mediated resistance against cytarabine + daunorubicin. Cytarabine MCL1 apoptosis regulator, BCL2 family member Homo sapiens