Metformin

MCL1 apoptosis regulator, BCL2 family member ; Homo sapiens







12 Article(s)
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PMID
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Pub. Year
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1 35427214 Metformin induces myeloma cells necrosis and apoptosis and it is considered for therapeutic use. 2022 Apr 15 1
2 35625692 Metformin Enhancement of Therapeutic Effects of 5-Fluorouracil and Oxaliplatin in Colon Cancer Cells and Nude Mice. 2022 Apr 20 1
3 34649197 Tumor-activatable biomineralized nanotherapeutics for integrative glucose starvation and sensitized metformin therapy. 2021 Nov 1
4 31031016 Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis. 2019 May 13 2
5 28345832 Metformin Inhibits Migration and Invasion of Cholangiocarcinoma Cells 2017 Feb 1 1
6 28881582 Metformin requires 4E-BPs to induce apoptosis and repress translation of Mcl-1 in hepatocellular carcinoma cells. 2017 Aug 1 3
7 26959881 Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1. 2016 Apr 5 1
8 27082123 Metformin induces apoptosis by microRNA-26a-mediated downregulation of myeloid cell leukaemia-1 in human oral cancer cells. 2016 Jun 5
9 27517746 Metformin enhances TRAIL-induced apoptosis by Mcl-1 degradation via Mule in colorectal cancer cells. 2016 Sep 13 13
10 25305450 Metformin displays anti-myeloma activity and synergistic effect with dexamethasone in in vitro and in vivo xenograft models. 2015 Jan 28 1
11 25542900 Targeting the metabolic plasticity of multiple myeloma with FDA-approved ritonavir and metformin. 2015 Mar 1 1
12 26056043 Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2. 2015 Aug 28 1