| 1 |
33906557 | How autophagy controls the intestinal epithelial barrier. | 2022 Jan |
1 |
| 2 |
34751006 | AKT controls protein synthesis and oxidative metabolism via combined mTORC1 and FOXO1 signalling to govern muscle physiology. | 2022 Feb |
1 |
| 3 |
34988938 | PI3K inhibition by BKM120 results in anti-proliferative effects on corticotroph tumor cells. | 2022 May |
1 |
| 4 |
35202857 | Minoxidil-loaded hyaluronic acid dissolving microneedles to alleviate hair loss in an alopecia animal model. | 2022 Apr 15 |
1 |
| 5 |
35344847 | Chemokine CXCL10 regulates pain behaviors via PI3K-AKT signaling pathway in mice. | 2022 Jun |
1 |
| 6 |
35532280 | AktAR and Akt-STOPS: Genetically Encodable Molecular Tools to Visualize and Perturb Akt Kinase Activity at Different Subcellular Locations in Living Cells. | 2022 May |
1 |
| 7 |
35565964 | Mechanistic Insights into the Ameliorating Effect of Melanogenesis of Psoralen Derivatives in B16F10 Melanoma Cells. | 2022 Apr 19 |
2 |
| 8 |
35576690 | AKAP12 ameliorates liver injury via targeting PI3K/AKT/PCSK6 pathway. | 2022 Jul |
2 |
| 9 |
35617801 | Medha Plus - A novel polyherbal formulation ameliorates cognitive behaviors and disease pathology in models of Alzheimer's disease. | 2022 Jul |
1 |
| 10 |
33189893 | A Novel PAK1-Notch1 Axis Regulates Crypt Homeostasis in Intestinal Inflammation. | 2021 |
1 |
| 11 |
33226552 | Potential role of TrkB agonist in neuronal survival by promoting CREB/BDNF and PI3K/Akt signaling in vitro and in vivo model of 3-nitropropionic acid (3-NP)-induced neuronal death. | 2021 Feb |
1 |
| 12 |
33468664 | Mdm2 phosphorylation by Akt regulates the p53 response to oxidative stress to promote cell proliferation and tumorigenesis. | 2021 Jan 26 |
1 |
| 13 |
33469368 | Up-Regulation of circEIF6 Contributes to Pancreatic Cancer Development Through Targeting miR-557/SLC7A11/PI3K/AKT Signaling. | 2021 |
1 |
| 14 |
33839150 | Insulin receptor substrate 1, but not IRS2, plays a dominant role in regulating pancreatic alpha cell function in mice. | 2021 Jan-Jun |
1 |
| 15 |
33869980 | Removal of Epididymal Visceral Adipose Tissue Prevents Obesity-Induced Multi-organ Insulin Resistance in Male Mice. | 2021 May 1 |
1 |
| 16 |
33985544 | AKT-mediated phosphorylation of Sox9 induces Sox10 transcription in a murine model of HER2-positive breast cancer. | 2021 May 13 |
1 |
| 17 |
34014413 | Serum-derived exosomes accelerate scald wound healing in mice by optimizing cellular functions and promoting Akt phosphorylation. | 2021 Aug |
1 |
| 18 |
34068807 | VEGF Mediates Retinal Müller Cell Viability and Neuroprotection through BDNF in Diabetes. | 2021 May 10 |
1 |
| 19 |
34082428 | Pioglitazone Enhances β-Arrestin2 Signaling and Ameliorates Insulin Resistance in Classical Insulin Target Tissues. | 2021 |
1 |
| 20 |
34331233 | Mutant Huntingtin Impairs Pancreatic β-cells by Recruiting IRS-2 and Disturbing the PI3K/AKT/FoxO1 Signaling Pathway in Huntington's Disease. | 2021 Dec |
1 |
| 21 |
34465724 | NOTCH1 signaling promotes protein stability of HER3 through the AKT pathway in squamous cell carcinoma of head and neck. | 2021 Aug 31 |
1 |
| 22 |
34666331 | The Synergistic Inhibitory Effect of Combining MK-2206 and AZD 6244 in MARIMO Cells Harboring a Calreticulin Gene Mutation. | 2021 |
1 |
| 23 |
34695518 | Fisetin-induced PTEN expression reverses cellular senescence by inhibiting the mTORC2-Akt Ser473 phosphorylation pathway in vascular smooth muscle cells. | 2021 Dec |
1 |
| 24 |
34769428 | Oleanolic Acid Alleviates Atopic Dermatitis-like Responses In Vivo and In Vitro. | 2021 Nov 5 |
1 |
| 25 |
34848742 | Endogenous regulation of the Akt pathway by the aryl hydrocarbon receptor (AhR) in lung fibroblasts. | 2021 Nov 30 |
1 |
| 26 |
34917687 | Caveolin-1 Is Essential for the Improvement of Insulin Sensitivity through AKT Activation during Glargine Treatment on Diabetic Mice. | 2021 |
1 |
| 27 |
31215069 | NAD(P)H Quinone Dehydrogenase 1 Ablation Inhibits Activation of the Phosphoinositide 3-Kinase/Akt Serine/Threonine Kinase and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Pathways and Blocks Metabolic Adaptation in Hepatocellular Carcinoma. | 2020 Feb |
1 |
| 28 |
31936236 | IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β-Nrf2-BNIP3 Pathway. | 2020 Jan 8 |
1 |
| 29 |
31981662 | Hypoglycaemic effect and mechanism of an RG-II type polysaccharide purified from Aconitum coreanum in diet-induced obese mice. | 2020 Apr 15 |
1 |
| 30 |
32144123 | NO-Releasing Nanoparticles Ameliorate Detrusor Overactivity in Transgenic Sickle Cell Mice via Restored NO/ROCK Signaling. | 2020 May |
1 |
| 31 |
32312949 | Loss of AKAP1 triggers Drp1 dephosphorylation-mediated mitochondrial fission and loss in retinal ganglion cells. | 2020 Apr 20 |
1 |
| 32 |
32432228 | Insulin Signal Transduction is Impaired in the Type 2 Diabetic Retina. | 2020 |
1 |
| 33 |
32450252 | Mdm2-mediated ubiquitination of β-arrestin2 in the nucleus occurs in a Gβγ- and clathrin-dependent manner. | 2020 Aug |
1 |
| 34 |
32531473 | Memantine Improves Depressive-like Behaviors via Kir6.1 Channel Inhibition in Olfactory Bulbectomized Mice. | 2020 Aug 21 |
2 |
| 35 |
32566257 | Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation. | 2020 |
1 |
| 36 |
32786820 | Ovotransferrin Exhibits Osteogenic Activity Partially via Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Activation in MC3T3-E1 Cells. | 2020 Sep 2 |
1 |
| 37 |
33240105 | Regulation of HCN2 Current by PI3K/Akt Signaling. | 2020 |
1 |
| 38 |
33328854 | Electroacupuncture Protects Cognition by Regulating Tau Phosphorylation and Glucose Metabolism via the AKT/GSK3β Signaling Pathway in Alzheimer's Disease Model Mice. | 2020 |
1 |
| 39 |
30362584 | Prolonged high-glucose exposure decreased SREBP-1/FASN/ACC in Schwann cells of diabetic mice via blocking PI3K/Akt pathway. | 2019 Apr |
1 |
| 40 |
30592148 | Transcriptome analysis of differentially expressed genes and pathways associated with mitoxantrone treatment prostate cancer. | 2019 Mar |
2 |
| 41 |
30734931 | Pink1 regulates FKBP5 interaction with AKT/PHLPP and protects neurons from neurotoxin stress induced by MPP. | 2019 Aug |
1 |
| 42 |
30885348 | PTEN inactivation induces epithelial-mesenchymal transition and metastasis by intranuclear translocation of β-catenin and snail/slug in non-small cell lung carcinoma cells. | 2019 Apr |
1 |
| 43 |
30975706 | HBx-K130M/V131I Promotes Liver Cancer in Transgenic Mice via AKT/FOXO1 Signaling Pathway and Arachidonic Acid Metabolism. | 2019 Jul |
1 |
| 44 |
30980895 | Tripeptide IRW initiates differentiation in osteoblasts differentiation via the RUNX2 pathway. | 2019 Jun |
1 |
| 45 |
30984553 | Vascular leakage caused by loss of Akt1 is associated with impaired mural cell coverage. | 2019 Apr |
1 |
| 46 |
31205027 | Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure. | 2019 Jun 17 |
1 |
| 47 |
31272455 | Matrix metalloproteinase activity in the lung is increased in Hermansky-Pudlak syndrome. | 2019 Jul 4 |
1 |
| 48 |
31461543 | Dock5 is a new regulator of microtubule dynamic instability in osteoclasts. | 2019 Nov |
1 |
| 49 |
31852639 | [Sepsis impairs aggregation of nicotinic acetylcholine receptors on murine skeletal muscle cell membranes by inhibiting AKT/GSK3β phosphorylation]. | 2019 Nov 30 |
1 |
| 50 |
27966074 | Brain-Defective Insulin Signaling Is Associated to Late Cognitive Impairment in Post-Septic Mice. | 2018 Jan |
1 |