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30399481 | Investigation on drug-binding in heme pocket of CYP2C19 with UV-visible and resonance Raman spectroscopies. | 2019 Feb 15 |
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22765278 | Effect of peginterferon alfa-2a (40KD) on cytochrome P450 isoenzyme activity. | 2013 Feb |
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21198441 | An in vitro, high throughput, seven CYP cocktail inhibition assay for the evaluation of new chemical entities using LC-MS/MS. | 2011 Jan |
1 |
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11956503 | Acute hypoxia and cytochrome P450-mediated hepatic drug metabolism in humans. | 2002 Apr |
1 |
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11037108 | Characterization of transgenic mouse strains using six human hepatic cytochrome P450 probe substrates. | 2000 Aug |
2 |
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3 |
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8861658 | Investigation of xenobiotic metabolism by CYP2D6 and CYP2C19: importance of enantioselective analytical methods. | 1996 Mar 29 |
1 |
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7704038 | Lack of low Km diazepam N-demethylase in livers of poor metabolizers for S-mephenytoin 4'-hydroxylation. | 1994 Dec |
2 |
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8454228 | [Genetic polymorphism in human drug metabolism]. | 1993 Feb |
2 |
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1441599 | Polymorphism in stereoselective hydroxylations of mephenytoin and hexobarbital by Japanese liver samples in relation to cytochrome P-450 human-2 (IIC9). | 1992 Sep-Oct |
2 |
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1857342 | Separation of human liver microsomal tolbutamide hydroxylase and (S)-mephenytoin 4'-hydroxylase cytochrome P-450 enzymes. | 1991 Jul |
1 |
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2669966 | Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae. | 1989 Jun 13 |
1 |
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2910639 | Propranolol's metabolism is determined by both mephenytoin and debrisoquin hydroxylase activities. | 1989 Jan |
1 |
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2827463 | Human cytochrome P-450 PB-1: a multigene family involved in mephenytoin and steroid oxidations that maps to chromosome 10. | 1988 Jan |
1 |
| 15 |
3196692 | Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4'-hydroxylase. | 1988 Sep 6 |
1 |
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3032244 | Cloning and sequence determination of a complementary DNA related to human liver microsomal cytochrome P-450 S-mephenytoin 4-hydroxylase. | 1987 Feb 24 |
1 |
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3442670 | Genetic polymorphism of human cytochrome P-450 (S)-mephenytoin 4-hydroxylase. Studies with human autoantibodies suggest a functionally altered cytochrome P-450 isozyme as cause of the genetic deficiency. | 1987 Dec 15 |
3 |
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3598900 | Hepatic metabolism of tolbutamide: characterization of the form of cytochrome P-450 involved in methyl hydroxylation and relationship to in vivo disposition. | 1987 Jun |
1 |
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2874666 | The molecular mechanisms of two common polymorphisms of drug oxidation--evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation. | 1986 May |
2 |
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3096378 | Mephenytoin-type polymorphism of drug oxidation: purification and characterization of a human liver cytochrome P-450 isozyme catalyzing microsomal mephenytoin hydroxylation. | 1986 Dec 10 |
5 |
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3709029 | Polymorphic metabolism of mephenytoin in man: pharmacokinetic interaction with a co-regulated substrate, mephobarbital. | 1986 Jun |
1 |
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4053486 | Mephenytoin hydroxylation polymorphism: characterization of the enzymatic deficiency in liver microsomes of poor metabolizers phenotyped in vivo. | 1985 Nov |
2 |
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6697650 | Sparteine oxidation by the human liver: absence of inhibition by mephenytoin. | 1984 Mar |
1 |
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1021219 | Binding of anticonvulsant drugs to cytochrome P-450: correlation with evidence of induction of hepatic microsomal enzymes. | 1976 Dec |
1 |