Title : Sparteine oxidation by the human liver: absence of inhibition by mephenytoin.

Pub. Date : 1984 Mar

PMID : 6697650






1 Functional Relationships(s)
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1 We used human liver preparations to test whether mephenytoin competes with sparteine for binding to the genetically variable cytochrome P-450, which mediates metabolism of both sparteine and debrisoquine. Mephenytoin cytochrome P450 family 4 subfamily F member 3 Homo sapiens