Title : Acute hypoxia and cytochrome P450-mediated hepatic drug metabolism in humans.

Pub. Date : 2002 Apr

PMID : 11956503






1 Functional Relationships(s)
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1 CYP enzyme activities were measured by means of the metabolic ratios of sparteine (CYP2D6), endogenous cortisol metabolism (CYP3A4), and caffeine (CYP1A2), as well as by the S/R ratio of mephenytoin (CYP2C19) and antipyrine clearance. Mephenytoin cytochrome P450 family 4 subfamily F member 3 Homo sapiens