Benzo(a)pyrene

cytochrome P450 family 4 subfamily F member 3 ; Homo sapiens







22 Article(s)
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1 31111189 The Toll-like receptor agonist imiquimod is metabolized by aryl hydrocarbon receptor-regulated cytochrome P450 enzymes in human keratinocytes and mouse liver. 2019 Jul 4
2 29921510 The regulation mechanism of AhR activated by benzo[a]pyrene for CYP expression are different between 2D and 3D culture of human lung cancer cells. 2018 Aug 1
3 28701518 Effect of Cytochrome P450 Metabolites of Arachidonic Acid in Nephrology. 2017 Oct 1
4 24372170 Degradation of benzo[a]pyrene by bacterial isolates from human skin. 2014 Apr 2
5 22155354 Multidrug resistance protein (MRP) 4 attenuates benzo[a]pyrene-mediated DNA-adduct formation in human bronchoalveolar H358 cells. 2012 Feb 25 2
6 20399842 The critical DNA damage by benzo(a)pyrene in lung tissues of smokers and approaches to preventing its formation. 2010 Sep 15 2
7 17967930 Sulfotransferase forms expressed in human intestinal Caco-2 and TC7 cells at varying stages of differentiation and role in benzo[a]pyrene metabolism. 2008 Feb 1
8 17237483 Growth kinetics in MCF-7 cells modulate benzo[a]pyrene-induced CYP1A1 up-regulation. 2007 Mar 4
9 21783461 Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity. 2005 Jan 2
10 14729370 Metabolic activation of 10-aza-substituted benzo[a]pyrene by cytochrome P450 1A2 in human liver microsomes. 2004 Feb 14 2
11 12227954 Systemic uptake and cutaneous disposition of pentachlorophenol in a sequential exposure scenario: effects of skin preexposure to benzo[a]pyrene. 2002 Sep 27 1
12 8507205 The catalytic activity of four expressed human cytochrome P450s towards benzo[a]pyrene and the isomers of its proximate carcinogen. 1993 May 14 1
13 2509067 Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons. 1989 Nov 15 1
14 2512389 Comparison of the formation of benzo[a]pyrene diolepoxide-DNA adducts in vitro by rat and human microsomes: evidence for the involvement of P-450IA1 and P-450IA2. 1989 Summer 2
15 2882985 Biotransformation of caffeine, paraxanthine, theophylline, and theobromine by polycyclic aromatic hydrocarbon-inducible cytochrome(s) P-450 in human liver microsomes. 1987 Mar-Apr 1
16 3697359 Conformational change of cytochrome P-450 indicated by the measurement of fluorescence-energy transfer. 1986 Apr 22 2
17 6088105 The generation of oxidation products of benzo[a]pyrene by lipid peroxidation: a study using gamma-irradiation. 1984 Sep 1
18 6477826 Inducibility of arylhydrocarbon-hydroxylase activity in human hair follicles by topical application of liquor carbonis detergens (coal tar). 1984 Sep 1
19 6626210 Induction of benzo(a)pyrene hydroxylase in Aspergillus ochraceus TS: evidences of multiple forms of cytochrome P-450. 1983 Sep 15 2
20 6285672 Interindividual variation in benzo(a)pyrene metabolism and composition of isoenzymes of cytochrome P-450 as revealed by SDS-gel electrophoresis of human liver microsomal fractions. 1982 Apr 1
21 6105054 Correlations between cytochrome P-450 and oxidative metabolism of benzo[a]pyrene and 7-ethoxycoumarin in human liver in vitro and antipyrine elimination in vivo. 1980 Jul-Aug 1
22 719999 The nature of hepatic cytochrone P-450 induced in hexachlorobenzene-fed rats. 1978 Nov 2