Phenobarbital

cytochrome P450 family 4 subfamily F member 3 ; Homo sapiens







100 Article(s)
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1 30689138 Should Cytochrome P450 Inducers be Used to Accelerate Clearance of Brodifacoum from Poisoned Patients? 2019 Mar 3
2 29357810 Cytochrome P450 1A2 Messenger RNA is a More Reliable Marker than Cytochrome P450 1A2 Activity, Phenacetin O-Deethylation, for Assessment of Induction Potential of Drug-Metabolizing Enzymes Using HepaRG Cells. 2018 2
3 28215634 Isolation and expansion of human pluripotent stem cell-derived hepatic progenitor cells by growth factor defined serum-free culture conditions. 2017 Mar 15 1
4 28856745 Using known drug interactions to manage supratherapeutic calcineurin inhibitor concentrations. 2017 Nov 1
5 27490534 The Impact of Anti-Epileptic Drugs on Growth and Bone Metabolism. 2016 Aug 1 4
6 25336106 HepG2 cells as an in vitro model for evaluation of cytochrome P450 induction by xenobiotics. 2015 1
7 21564387 Children on phenobarbital monotherapy requires more sedatives during MRI. 2011 Oct 1
8 21098752 Phenobarbital/Lamotrigine coadministration-induced blood dyscrasia in a patient with epilepsy. 2010 Dec 1
9 19420747 Induction of drug-metabolizing enzymes by phenobarbital in layered co-culture of a human liver cell line and endothelial cells. 2009 May 2
10 18803983 Drug interactions between chemotherapeutic regimens and antiepileptics. 2008 Aug 2
11 16487217 Clinically relevant drug interactions with antiepileptic drugs. 2006 Mar 2
12 16867264 Influences of 3-methylcholanthrene, phenobarbital and dexamethasone on xenobiotic metabolizing-related cytochrome P450 enzymes and steroidogenesis in human fetal adrenal cortical cells. 2006 Aug 2
13 15038401 [Drug interactions with antiepileptic agents]. 2004 Feb 28 1
14 15135080 Steroid hormone biotransformation and xenobiotic induction of hepatic steroid metabolizing enzymes. 2004 Apr 15 1
15 15382119 Interleukin 1beta inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance. 2004 Oct 1
16 12739762 Induction of cytochrome P450 2B6 and 3A4 expression by phenobarbital and cyclophosphamide in cultured human liver slices. 2003 Apr 1
17 11967242 Methoxyestradiols mediate estradiol-induced antimitogenesis in human aortic SMCs. 2002 Apr 2
18 10757780 The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR. 2000 May 1
19 10522495 Effects of pretreatment with cytochrome P-450 inducers, especially phenobarbital on triphenyltin metabolism and toxicity in hamsters. 1999 Oct 1 7
20 9606477 A mechanistic approach to antiepileptic drug interactions. 1998 May 1
21 9872399 The influence of phenobarbital on cytochromes and reactive oxygen species in erythropoietin producing HepG2 cells. 1998 Dec 4 1
22 8907578 Modulation of constitutive and inducible hepatic cytochrome(s) P-450 by interferon beta in mice. 1996 Feb 1
23 7713363 Effect of nifedipine, verapamil and diltiazem on the enzyme-inducing activity of phenobarbital and beta-naphthoflavone. 1995 Jan 1
24 8082573 Regulatory mechanisms in the activation of nitrogenous compounds by mammalian cytochrome P-450 isozymes. 1994 1
25 8447722 Microsomal N-oxygenation of adenine to adenine 1-N-oxide. 1993 Jan 1
26 8452565 Cytochrome P450 isoforms in human fetal tissues related to phenobarbital-inducible forms in the mouse. 1993 Feb 24 1
27 1536639 Phenobarbital induction of cytochrome P-450 gene expression. 1992 Feb 1 1
28 1808966 [Effect of levonorgestrel and ethinyl estradiol and their combination on biotransformation reactions]. 1991 1
29 1819909 Effect of nifedipine on the enzyme-inducing activity of phenobarbital and beta-naphthoflavone. 1991 1
30 1914510 Immunocytochemical study of phenobarbital- and 3-methylcholanthrene-inducible cytochrome P450 isozymes in primary cultures of porcine ciliary epithelium. 1991 Aug 1
31 1949908 Metabolism of the chloroethylnitrosoureas. 1991 Jun 1
32 2268369 Immunochemical detection of human liver cytochrome P450 forms related to phenobarbital-inducible forms in the mouse. 1990 Dec 1 1
33 2597175 Absence of an isotope effect in induction of cytochrome P-450 and xenobiotic metabolizing enzyme activities by stable isotope-labelled phenobarbital isotopomers. 1989 Nov 1 1
34 2634093 Adverse reactions of imidazole antifungal agents: computer graphic studies of cytochrome P-450 interactions. 1989 Winter 1
35 2744145 [The immunotropic activity of GABA during cytochrome P-450 induction in the liver]. 1989 Mar-Apr 1
36 2917006 Induction and depression of cytochrome P-450-dependent mixed-function oxidase by a cloned consensus alpha-interferon (IFN-alpha CON1) in the hamster. 1989 Feb 1 1
37 3135288 Influence of phenobarbital dosage, dietary crude protein level and interval to measurement on hepatic monoxygenase activity in ewes. 1988 Jun 1
38 3243187 In vitro effects of polyhalogenated hydrocarbons on liver mitochondria respiration and microsomal cytochrome P-450. 1988 1
39 3337745 Metabolic activation of environmental carcinogens and mutagens by human liver microsomes. Role of cytochrome P-450 homologous to a 3-methylcholanthrene-inducible isozyme in rat liver. 1988 Feb 1 2
40 3356413 Phenobarbital induction of cytochrome P-450 b,e genes is dependent on protein synthesis. 1988 Mar-Apr 8
41 3445541 [Effect of different inactivating agents on microsomal cytochromes P-450 and P-448]. 1987 Nov-Dec 1
42 3628472 Mechanisms of phenobarbital-type induction of cytochrome P-450 isozymes. 1987 1
43 3663765 [Directed modification of the structure of cytochrome P-450 substrates as a method of generating new inducers of the microsomal monooxygenase system]. 1987 Aug 1
44 3671445 [The effect of intrahepatic cholestasis in pregnancy on various forms of cytochrome P-450-dependent biotransformation reactions]. 1987 May 1
45 3810888 [Factors regulating mono-oxygenase induction by phenobarbital xenobiotics]. 1987 Jan-Feb 1
46 2425812 Induction of sister chromatid exchanges in human and rat hepatoma cell lines by cyclophosphamide and phosphoramide mustard and the effects of cytochrome P-450 inhibitors. 1986 Jul 1 1
47 2425856 [Induction of the phenobarbital form of cytochrome P-450 by chemically unrelated compounds]. 1986 Jul 6
48 3022748 Differential effects of the cytochrome P-450/reductase ratio on the oxidation of ethanol and the hydroxyl radical scavenging agent 2-keto-4-thiomethylbutyric acid (KMBA). 1986 Nov 15 1
49 3082822 A comparative study of the mutagenic activation of N-nitrosopropylamines by various animal species and man: evidence for a cytochrome P-450 dependent reaction. 1986 Feb 1
50 3481957 Regional localization of a human cytochrome P-450 (CYP1) to chromosome 19q13.1-13.3. 1986 Jul 1