Title : The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR.

Pub. Date : 2000 May

PMID : 10757780






1 Functional Relationships(s)
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1 However, CAR transactivation is increased in the presence of 1,4-bis[2-(3, 5-dichloropyridyloxy)]benzene (TCPOBOP), the most potent known member of the phenobarbital-like class of CYP-inducing agents. Phenobarbital cytochrome P450 family 4 subfamily F member 3 Homo sapiens