Phenytoin

cytochrome P450 family 2 subfamily C member 9 ; Homo sapiens







152 Article(s)
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1 35062050 CYP450 drug inducibility in NAFLD via an in vitro hepatic model: Understanding drug-drug interactions in the fatty liver. 2022 Feb 1
2 35426132 The Impact of CYP2C9*11 Allelic Variant on the Pharmacokinetics of Phenytoin and (S)-Warfarin. 2022 Jul 3
3 35590072 Exome sequencing allows detection of relevant pharmacogenetic variants in epileptic patients. 2022 May 19 1
4 35629204 Frequency of CYP2C9 Promoter Variable Number Tandem Repeat Polymorphism in a Spanish Population: Linkage Disequilibrium with CYP2C9*3 Allele. 2022 May 12 1
5 32779747 Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C9 and HLA-B Genotypes and Phenytoin Dosing: 2020 Update. 2021 Feb 2
6 33961833 Risk prediction of drug-drug interaction potential of phenytoin and miconazole topical formulations. 2021 Jul 1 2
7 34060344 A meta-analysis of effects of CYP2C9 and CYP2C19 polymorphisms on phenytoin pharmacokinetic parameters. 2021 Jul 3
8 34109627 PharmVar GeneFocus: CYP2C9. 2021 Sep 1
9 34429480 Impact of genetic and non-genetic factors on hepatic CYP2C9 expression and activity in Hungarian subjects. 2021 Aug 24 1
10 31646624 HLA-B*51:01 and CYP2C9*3 Are Risk Factors for Phenytoin-Induced Eruption in the Japanese Population: Analysis of Data From the Biobank Japan Project. 2020 May 4
11 31938857 Phenytoin intoxication associated with omeprazole administration in a child with defective CYP2C9. 2020 May 3
12 32216088 Associations of CYP2C9 and CYP2C19 Pharmacogenetic Variation with Phenytoin-Induced Cutaneous Adverse Drug Reactions. 2020 Sep 3
13 32423989 Heterologous Expression and Functional Characterization of Novel CYP2C9 Variants Identified in the Alaska Native People. 2020 Aug 1
14 32457604 Possible Genetic Determinants of Response to Phenytoin in a Group of Colombian Patients With Epilepsy. 2020 1
15 32510242 An update on CYP2C9 polymorphisms and phenytoin metabolism: implications for adverse effects. 2020 Aug 5
16 33071782 Comparison of CYP2C9 Activity in Ethiopian and Non-Ethiopian Jews Using Phenytoin as a Probe. 2020 2
17 33967488 How genetic variation was analyzed in phenytoin-induced gingival enlargement using single-nucleotide polymorphism of candidate gene CYP2C9? 2020 Sep-Dec 2
18 30270535 HLA Alleles and CYP2C9*3 as Predictors of Phenytoin Hypersensitivity in East Asians. 2019 Feb 4
19 31206740 High and variable population prevalence of HLA-B*56:02 in indigenous Australians and relation to phenytoin-associated drug reaction with eosinophilia and systemic symptoms. 2019 Sep 1
20 31461080 Assessing the clinical impact of CYP2C9 pharmacogenetic variation on phenytoin prescribing practice and patient response in an integrated health system. 2019 Oct 4
21 29274302 Association of CYP2C9*3 with phenytoin-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: A systematic review and meta-analysis. 2018 Jun 5
22 29628024 The association between CYP2C9/2C19 polymorphisms and phenytoin maintenance doses in Asian epileptic patients: A systematic review and meta-analysis
. 2018 Jul 5
23 29636628 CYP2C9 polymorphisms in epilepsy: influence on phenytoin treatment. 2018 5
24 30135636 The role of pharmacogenetics of cytochrome P450s in phenytoin-induced DRESS syndrome. 2018 1
25 30283820 DRESS after IV phenytoin associated with cytochrome P450 CYP2C9*3 homozygosity. 2018 Oct 1
26 28302415 A prospective study to assess the association between genotype, phenotype and Prakriti in individuals on phenytoin monotherapy. 2017 Jan - Mar 1
27 28748348 Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region. 2017 Sep 1
28 28820457 Role of CYP2C9, CYP2C19 and EPHX Polymorphism in the Pharmacokinetic of Phenytoin: A Study on Uruguayan Caucasian Subjects. 2017 Aug 18 3
29 29472822 Presence of a single nucleotide polymorphism (RS3758581) in a boy with DRESS syndrome. 2017 1
30 25998968 Phenytoin toxicity in two-month-old Thai infant with CYP2C9 gene polymorphism--A case report. 2016 Jan 3
31 26122019 CYP2C9, CYP2C19, ABCB1 genetic polymorphisms and phenytoin plasma concentrations in Mexican-Mestizo patients with epilepsy. 2016 Jun 1
32 26658169 Phenytoin neurotoxicity in a child carrying new STXBP1 and CYP2C9 gene mutations. 2016 Jan 1
33 26928377 Associations between HLA class I and cytochrome P450 2C9 genetic polymorphisms and phenytoin-related severe cutaneous adverse reactions in a Thai population. 2016 May 3
34 27154258 Severe cutaneous adverse drug reactions. 2016 Jul 1
35 27163851 In vitro metabolism of phenytoin in 36 CYP2C9 variants found in the Chinese population. 2016 Jun 25 8
36 27174459 Population Pharmacokinetics of Phenytoin Based on NONMEM in Patients with Intracranial Tumor During the First Week of Post-Craniotomy. 2016 1
37 27179628 Frequencies of CYP2C9 polymorphisms in North Indian population and their association with drug levels in children on phenytoin monotherapy. 2016 May 14 3
38 27390048 Pharmacokinetic model analysis of interaction between phenytoin and capecitabine. 2016 Sep 1
39 25162219 Individualized phenytoin therapy for Japanese pediatric patients with epilepsy based on CYP2C9 and CYP2C19 genotypes. 2015 Apr 3
40 25311916 The effect of polymorphic metabolism enzymes on serum phenytoin level. 2015 Mar 1
41 25597548 Use of multi-dose activated charcoal in phenytoin toxicity secondary to genetic polymorphism. 2015 Feb 1
42 25681367 [A case of phenytoin intoxication caused by interaction between phenytoin and capecitabine]. 2015 Feb 1
43 25943175 Clinical relevance of genetic polymorphism in CYP2C9 gene to pharmacodynamics and pharmacokinetics of phenytoin in epileptic patients: validatory pharmacogenomic approach to pharmacovigilance. 2015 Jul 3
44 25994870 Association analysis of CYP2C9*3 and phenytoin-induced severe cutaneous adverse reactions (SCARs) in Thai epilepsy children. 2015 Aug 5
45 26037375 CYP2C9 polymorphisms and phenytoin metabolism: implications for adverse effects. 2015 5
46 26179835 Potentially Unsafe Herb-drug Interactions Between a Commercial Product of Noni Juice and Phenytoin- A Case Report. 2015 Jun 1
47 24530212 Influence of CYP2C9 polymorphism and phenytoin co-administration on acenocoumarol dose in patients with cerebral venous thrombosis. 2014 May 1
48 24825094 Molecular functionality of CYP2C9 polymorphisms and their influence on drug therapy. 2014 1
49 25096692 Genetic variants associated with phenytoin-related severe cutaneous adverse reactions. 2014 Aug 6 5
50 25099164 Clinical pharmacogenetics implementation consortium guidelines for CYP2C9 and HLA-B genotypes and phenytoin dosing. 2014 Nov 3