Phenobarbital

cytochrome P450 family 2 subfamily C member 9 ; Homo sapiens







20 Article(s)
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Pub. Year
#Total Relationships
1 26496779 Clinical Pharmacology of Phenobarbital in Neonates: Effects, Metabolism and Pharmacokinetics. 2016 1
2 20509749 Expression and inducibility by phenobarbital of CYP2C33, CYP2C42, CYP2C49, CYP2B22, and CYP3As in porcine liver, kidney, small intestine, and nasal tissues. 2010 Aug 2
3 27713373 Update on the Genetic Polymorphisms of Drug-Metabolizing Enzymes in Antiepileptic Drug Therapy. 2010 Aug 20 1
4 19202563 Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes. 2009 Jan-Feb 1
5 19515014 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. 2009 2
6 17304159 Population estimation of the effects of cytochrome P450 2C9 and 2C19 polymorphisms on phenobarbital clearance in Japanese. 2007 Feb 5
7 16479536 Relative and absolute quantitative expression profiling of cytochromes P450 using isotope-coded affinity tags. 2006 Mar 1
8 15843486 Three-dimensional quantitative structure-activity relationship analysis of cytochromes p450: effect of incorporating higher-affinity ligands and potential new applications. 2005 Jul 1
9 14600250 Induction of human CYP2C9 by rifampicin, hyperforin, and phenobarbital is mediated by the pregnane X receptor. 2004 Feb 4
10 15382119 Interleukin 1beta inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance. 2004 Oct 1
11 15557548 Pharmacogenetics and enzyme induction/inhibition properties of antiepileptic drugs. 2004 Nov 23 1
12 11679585 Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor. 2002 Jan 4 2
13 12130704 Expression and induction of CYP2C P450 enzymes in primary cultures of human hepatocytes. 2002 Aug 1
14 12181452 Regulation of human CYP2C9 by the constitutive androstane receptor: discovery of a new distal binding site. 2002 Sep 3
15 11181490 Induction of CYP2C genes in human hepatocytes in primary culture. 2001 Mar 3
16 10712746 Phenobarbital increases DNA adduct and metabolites formed by ochratoxin A: role of CYP 2C9 and microsomal glutathione-S-transferase. 2000 1
17 10924340 Interleukin-6 negatively regulates the expression of pregnane X receptor and constitutively activated receptor in primary human hepatocytes. 2000 Aug 11 1
18 9663807 Cytochrome P4502C9: an enzyme of major importance in human drug metabolism. 1998 Jun 1
19 2200675 Expression of cytochrome P-450 enzymes in cultured human hepatocytes. 1990 Jul 31 1
20 20702214 Effects of various inducers on the expression of cytochromes P-450 IIC8, 9, 10 and IIIA in cultured adult human hepatocytes. 1990 1