Title : Potentiation of estrogen receptor activation function 1 (AF-1) by Src/JNK through a serine 118-independent pathway.

Pub. Date : 2001 Jan

PMID : 11145737






2 Functional Relationships(s)
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1 Expression of constitutively active Src or stimulation of the endogenous Src/JNK pathway enhances transcriptional activation by the estrogen-ER complex and strongly stimulates the otherwise weak activation by the unliganded ER and the tamoxifen-ER complex. Tamoxifen SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens
2 Expression of constitutively active Src or stimulation of the endogenous Src/JNK pathway enhances transcriptional activation by the estrogen-ER complex and strongly stimulates the otherwise weak activation by the unliganded ER and the tamoxifen-ER complex. Tamoxifen SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens