Crizotinib

ROS proto-oncogene 1, receptor tyrosine kinase ; Homo sapiens







268 Article(s)
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51 34660618 Case Report: Two Rare Cases of Complete Metabolic Response to Crizotinib in Patients With Rearranged ROS1 and ALK Metastatic Non-small Lung Cancer. 2021 4
52 34686712 Crizotinib efficacy in advanced non-squamous NSCLC patients with ALK or ROS1 rearrangement. 2021 Oct 22 2
53 34715804 Cost-effectiveness analysis of first-line treatment with crizotinib in ROS1-rearranged advanced non-small cell lung cancer (NSCLC) in Canada. 2021 Oct 29 3
54 31509456 Correlation of ROS1 Immunohistochemistry With ROS1 Fusion Status Determined by Fluorescence In Situ Hybridization. 2020 Jun 2
55 31607443 ROS1-rearranged Non-small-cell Lung Cancer is Associated With a High Rate of Venous Thromboembolism: Analysis From a Phase II, Prospective, Multicenter, Two-arms Trial (METROS). 2020 Jan 1
56 31778074 Dose-escalation trial of the ALK, MET & ROS1 inhibitor, crizotinib, in patients with advanced cancer. 2020 Jan 1
57 32143435 Reactive Oxygen Species (ROS)-Sensitive Prodrugs of the Tyrosine Kinase Inhibitor Crizotinib. 2020 Mar 4 1
58 32158297 Incidence of ROS1-Rearranged Non-Small-Cell Lung Carcinoma in India and Efficacy of Crizotinib in Lung Adenocarcinoma Patients. 2020 2
59 32167664 First-line crizotinib versus platinum-pemetrexed chemotherapy in patients with advanced ROS1-rearranged non-small-cell lung cancer. 2020 May 4
60 32168429 Crizotinib vs platinum-based chemotherapy as first-line treatment for advanced non-small cell lung cancer with different ROS1 fusion variants. 2020 May 3
61 32208297 A novel ROS1 G2032 K missense mutation mediates lorlatinib resistance in a patient with ROS1-rearranged lung adenocarcinoma but responds to nab-paclitaxel plus pembrolizumab. 2020 May 1
62 32232958 Effect of the patient information brochure in communicating the risks associated with crizotinib treatment to patients with non-small cell lung cancer (NSCLC) in Europe. 2020 Apr 1
63 32238411 Crizotinib in ROS1 and MET Deregulated NSCLC-Letter. 2020 Apr 1 1
64 32238412 Crizotinib in ROS1 and MET Deregulated NSCLC-Response. 2020 Apr 1 1
65 32269053 Repotrectinib Exhibits Potent Antitumor Activity in Treatment-Naïve and Solvent-Front-Mutant ROS1-Rearranged Non-Small Cell Lung Cancer. 2020 Jul 1 2
66 32409267 Treatment Patterns and Clinical Outcomes Among Patients With ROS1-rearranged Non-small-cell Lung Cancer Progressing on Crizotinib. 2020 Sep 4
67 32433811 A case of ROS1-rearranged lung adenocarcinoma exhibiting pleural effusion caused by crizotinib. 2020 Jul 2
68 32462394 Clinical activity of brigatinib in ROS1-rearranged non-small cell lung cancer. 2020 Dec 1
69 32577365 A case of ROS1-rearranged lung adenocarcinoma with osteoblastic bone metastasis. 2020 1
70 32590748 A novel TJP1-ROS1 fusion in malignant peripheral nerve sheath tumor responding to crizotinib: A case report. 2020 Jun 26 1
71 32591465 U.S. Phase I First-in-human Study of Taletrectinib (DS-6051b/AB-106), a ROS1/TRK Inhibitor, in Patients with Advanced Solid Tumors. 2020 Sep 15 2
72 32648475 Matching-adjusted indirect comparison: entrectinib versus crizotinib in ROS1 fusion-positive non-small cell lung cancer. 2020 Aug 1
73 32652753 Successful Treatment of Patients with Refractory High-Grade Serous Ovarian Cancer with GOPC-ROS1 Fusion Using Crizotinib: A Case Report. 2020 Nov 3
74 32702569 Effectiveness and prognostic factors of first-line crizotinib treatment in patients with ROS1-rearranged non-small cell lung cancer: A multicenter retrospective study. 2020 Sep 6
75 32776005 Cases of ROS1-rearranged lung cancer: when to use crizotinib, entrectinib, lorlatinib, and beyond? 2020 Jun 2
76 32792859 Chidamide increases the sensitivity of Non-small Cell Lung Cancer to Crizotinib by decreasing c-MET mRNA methylation. 2020 1
77 32865687 Efficacy and Safety of Crizotinib in the Treatment of Advanced Non-Small-Cell Lung Cancer with ROS1 Rearrangement or MET Alteration: A Systematic Review and Meta-Analysis. 2020 Oct 5
78 32871626 Molecular and clinicopathological characteristics of ROS1-rearranged non-small-cell lung cancers identified by next-generation sequencing. 2020 Nov 3
79 32882995 Novel Multitarget Therapies for Lung Cancer and Respiratory Disease. 2020 Sep 1 1
80 33116618 Identification of a Novel MPRIP-ROS1 Fusion and Clinical Efficacy of Crizotinib in an Advanced Lung Adenocarcinoma Patient: A Case Report. 2020 6
81 33172113 Focus on ROS1-Positive Non-Small Cell Lung Cancer (NSCLC): Crizotinib, Resistance Mechanisms and the Newer Generation of Targeted Therapies. 2020 Nov 6 5
82 33204104 A Novel ROS1-FBXL17 Fusion Co-Existing with CD74-ROS1 Fusion May Improve Sensitivity to Crizotinib and Prolong Progression-Free Survival of Patients with Lung Adenocarcinoma. 2020 10
83 33324391 ROS1 Fusion Mediates Immunogenicity by Upregulation of PD-L1 After the Activation of ROS1-SHP2 Signaling Pathway in Non-Small Cell Lung Cancer. 2020 1
84 33489827 How selecting best upfront therapy for metastatic disease?-Focus on ROS1-rearranged disease. 2020 Dec 2
85 30350109 Identification of a novel KLC1-ROS1 fusion in a case of pediatric low-grade localized glioma. 2019 Jan 1
86 30626830 Successful Treatment of ROS1-rearranged Lung Cancer Complicated by Hypertrophic Pulmonary Osteoarthropathy with Crizotinib Therapy. 2019 May 15 2
87 30642440 Case report: Crizotinib is effective in a patient with ROS1-rearranged pulmonary inflammatory myofibroblastic tumor. 2019 Feb 1
88 30642448 Exploration of germline variants responsible for adverse events of crizotinib in anaplastic lymphoma kinase-positive non-small cell lung cancer by target-gene panel sequencing. 2019 Feb 1
89 30664990 Molecular Analysis of Plasma From Patients With ROS1-Positive NSCLC. 2019 May 4
90 30719217 ROS1-GOPC/FIG: a novel gene fusion in hepatic angiosarcoma. 2019 Jan 4 2
91 30797499 Identification of a novel WNK1-ROS1 fusion in a lung adenocarcinoma sensitive to crizotinib. 2019 Mar 4
92 30867785 Clinicopathological features and clinical efficacy of crizotinib in Chinese patients with ROS1-positive non-small cell lung cancer. 2019 Mar 3
93 30915158 ROS1 mutation non-small cell lung cancer-access to optimal treatment and outcomes. 2019 2
94 30940295 Different Types of ROS1 Fusion Partners Yield Comparable Efficacy to Crizotinib. 2019 Aug 8 3
95 30976989 Crizotinib in Chinese Patients with ROS1-Rearranged Advanced Non‒Small-Cell Lung Cancer in Routine Clinical Practice. 2019 Jun 4
96 30978502 Safety and Efficacy of Crizotinib in Patients With Advanced or Metastatic ROS1-Rearranged Lung Cancer (EUCROSS): A European Phase II Clinical Trial. 2019 Jul 1
97 30980071 Crizotinib in ROS1-rearranged advanced non-small-cell lung cancer (NSCLC): updated results, including overall survival, from PROFILE 1001. 2019 Jul 1 2
98 31027745 Next-Generation Sequencer Analysis of Pulmonary Pleomorphic Carcinoma With a CD74-ROS1 Fusion Successfully Treated With Crizotinib. 2019 May 1
99 31085007 Histopathologic characteristics of advanced-stage ROS1-rearranged non-small cell lung cancers. 2019 Jul 1
100 31118681 High feasibility of cytological specimens for detection of ROS1 fusion by reverse transcriptase PCR in Chinese patients with advanced non-small-cell lung cancer. 2019 1