Title : Successful Treatment of Patients with Refractory High-Grade Serous Ovarian Cancer with GOPC-ROS1 Fusion Using Crizotinib: A Case Report.

Pub. Date : 2020 Nov

PMID : 32652753






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1 Successful Treatment of Patients with Refractory High-Grade Serous Ovarian Cancer with GOPC-ROS1 Fusion Using Crizotinib: A Case Report. Crizotinib ROS proto-oncogene 1, receptor tyrosine kinase Homo sapiens
2 CONCLUSION: This study suggested that crizotinib was an off-the-shelf, practical, and ostensibly effective treatment option for patients with ovarian cancer with ROS1 rearrangement. Crizotinib ROS proto-oncogene 1, receptor tyrosine kinase Homo sapiens
3 This study suggests that comprehensive sequencing should be offered for patients with ovarian cancer without effective therapeutic strategies, and crizotinib can be used to treat ROS1-rearranged ovarian carcinomas. Crizotinib ROS proto-oncogene 1, receptor tyrosine kinase Homo sapiens