ABT-737

phorbol-12-myristate-13-acetate-induced protein 1 ; Homo sapiens







13 Article(s)
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1 24525728 Noxa determines localization and stability of MCL-1 and consequently ABT-737 sensitivity in small cell lung cancer. 2014 Feb 13 1
2 25139025 Co-administration of ABT-737 and SAHA induces apoptosis, mediated by Noxa upregulation, Bax activation and mitochondrial dysfunction in PTEN-intact malignant human glioma cell lines. 2014 Dec 1
3 23344663 Platinum compounds sensitize ovarian carcinoma cells to ABT-737 by modulation of the Mcl-1/Noxa axis. 2013 Apr 2
4 23429261 pRb/E2F-1-mediated caspase-dependent induction of Noxa amplifies the apoptotic effects of the Bcl-2/Bcl-xL inhibitor ABT-737. 2013 May 2
5 23814486 PAX3-FOXO1 induces up-regulation of Noxa sensitizing alveolar rhabdomyosarcoma cells to apoptosis. 2013 Jul 1
6 22173547 Modulation of NOXA and MCL-1 as a strategy for sensitizing melanoma cells to the BH3-mimetic ABT-737. 2012 Feb 1 1
7 21897876 The combination of BH3-mimetic ABT-737 with the alkylating agent temozolomide induces strong synergistic killing of melanoma cells independent of p53. 2011 3
8 20576107 Chemotherapeutic drugs sensitize human renal cell carcinoma cells to ABT-737 by a mechanism involving the Noxa-dependent inactivation of Mcl-1 or A1. 2010 Jun 24 3
9 20732961 Actinomycin D decreases Mcl-1 expression and acts synergistically with ABT-737 against small cell lung cancer cell lines. 2010 Sep 1 1
10 18987671 BH3 mimetic ABT-737 and a proteasome inhibitor synergistically kill melanomas through Noxa-dependent apoptosis. 2009 Apr 2
11 19246337 ABT-737 synergizes with chemotherapy to kill head and neck squamous cell carcinoma cells via a Noxa-mediated pathway. 2009 May 1
12 19412422 Endogenous Noxa Determines the Strong Proapoptotic Synergism of the BH3-Mimetic ABT-737 with Chemotherapeutic Agents in Human Melanoma Cells. 2009 May 1
13 19088028 Induction of Noxa sensitizes human colorectal cancer cells expressing Mcl-1 to the small-molecule Bcl-2/Bcl-xL inhibitor, ABT-737. 2008 Dec 15 3