Tyrosine

von Willebrand factor ; Homo sapiens







47 Article(s)
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1 34461090 Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity. 2021 Oct 2
2 24097977 Interaction of Shiga toxin with the A-domains and multimers of von Willebrand Factor. 2013 Nov 15 1
3 21943193 Understanding FVIII/VWF complex--report from a symposium of XXIX WFH meeting 2010. 2012 May 2
4 19812385 Oxidative modification of von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13. 2010 Jan 21 1
5 20075158 Amino acid residues Arg(659), Arg(660), and Tyr(661) in the spacer domain of ADAMTS13 are critical for cleavage of von Willebrand factor. 2010 Mar 18 1
6 18492805 Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13. 2008 May 27 1
7 18492952 Extensive contacts between ADAMTS13 exosites and von Willebrand factor domain A2 contribute to substrate specificity. 2008 Sep 1 2
8 18502798 Mechanistic studies on ADAMTS13 catalysis. 2008 Sep 4
9 17393013 Altered von Willebrand factor subunit proteolysis and multimer processing associated with the Cys2362Phe mutation in the B2 domain. 2007 Apr 3
10 17539777 A familial platelet function disorder associated with abnormal signalling through the glycoprotein VI pathway. 2007 Jun 1
11 17540842 The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow. 2007 Sep 15 2
12 17610557 C1584 in von Willebrand factor is necessary for enhanced proteolysis by ADAMTS13 in vitro. 2007 Jul 2
13 16774914 Leucine-rich repeats 2-4 (Leu60-Glu128) of platelet glycoprotein Ibalpha regulate shear-dependent cell adhesion to von Willebrand factor. 2006 Sep 8 1
14 17121983 Characterization of a core binding site for ADAMTS-13 in the A2 domain of von Willebrand factor. 2006 Dec 5 3
15 17146059 Exosite interactions contribute to tension-induced cleavage of von Willebrand factor by the antithrombotic ADAMTS13 metalloprotease. 2006 Dec 12 1
16 15809291 Role of chloride ions in modulation of the interaction between von Willebrand factor and ADAMTS-13. 2005 Jun 17 4
17 15975930 The proximal carboxyl-terminal domains of ADAMTS13 determine substrate specificity and are all required for cleavage of von Willebrand factor. 2005 Aug 19 1
18 14525793 An amino acid polymorphism in von Willebrand factor correlates with increased susceptibility to proteolysis by ADAMTS13. 2004 Feb 1 2
19 15166929 Type 1 von Willebrand disease: a possible novel mechanism. 2004 May 2
20 15561695 Recent advances in thrombotic thrombocytopenic purpura. 2004 1
21 11756164 Functional analysis of the C-terminal flanking sequence of platelet glycoprotein Ib alpha using canine-human chimeras. 2002 Jan 1 1
22 11772401 Glycoprotein IIb-IIIa-dependent aggregation by glycoprotein Ibalpha is reinforced by a Src family kinase inhibitor (PP1)-sensitive signalling pathway. 2002 Jan 15 3
23 11802708 Pathological shear stress stimulates the tyrosine phosphorylation of alpha-actinin associated with the glycoprotein Ib-IX complex. 2002 Jan 29 1
24 11916084 Proline-rich tyrosine kinase 2 and focal adhesion kinase are involved in different phases of platelet activation by vWF. 2002 Mar 5
25 12036871 Site-directed mutagenesis of platelet glycoprotein Ib alpha demonstrating residues involved in the sulfation of tyrosines 276, 278, and 279. 2002 Jun 15 1
26 12105169 Involvement of glycoprotein VI in platelet thrombus formation on both collagen and von Willebrand factor surfaces under flow conditions. 2002 Jul 9 1
27 11279169 Tyrosine sulfation of glycoprotein I(b)alpha. Role of electrostatic interactions in von Willebrand factor binding. 2001 May 18 1
28 11341505 Fc-receptor dependent platelet aggregation induced by monoclonal antibodies against platelet glycoprotein Ib or von Willebrand factor. 2001 Apr 1
29 11344169 Platelet activation by von Willebrand factor requires coordinated signaling through thromboxane A2 and Fc gamma IIA receptor. 2001 Jul 13 2
30 11389024 Role of Fc receptor gamma-chain in platelet glycoprotein Ib-mediated signaling. 2001 Jun 15 4
31 10648402 Requirement of leucine-rich repeats of glycoprotein (GP) Ibalpha for shear-dependent and static binding of von Willebrand factor to the platelet membrane GP Ib-IX-V complex. 2000 Feb 1 1
32 10777573 Modeling and functional analysis of the interaction between von Willebrand factor A1 domain and glycoprotein Ibalpha. 2000 Apr 28 1
33 10805282 Platelet activation mediated through membrane glycoproteins: involvement of tyrosine kinases. 2000 1
34 11113273 Adrenaline potentiates type 2B von Willebrand factor-induced activation of human platelets by enhancing both the formation and action of thromboxanes. 2000 Nov 15 1
35 10224142 Rap1B and Rap2B translocation to the cytoskeleton by von Willebrand factor involves FcgammaII receptor-mediated protein tyrosine phosphorylation. 1999 May 7 3
36 9076944 Molecular mechanisms of platelet adhesion and activation. 1997 Jan 2
37 9215757 Crystal structure of NMC-4 fab anti-von Willebrand factor A1 domain. 1997 1
38 9389695 Glycoprotein Ib-von Willebrand factor interactions activate tyrosine kinases in human platelets. 1997 Dec 15 1
39 8664285 Mocarhagin, a novel cobra venom metalloproteinase, cleaves the platelet von Willebrand factor receptor glycoprotein Ibalpha. Identification of the sulfated tyrosine/anionic sequence Tyr-276-Glu-282 of glycoprotein Ibalpha as a binding site for von Willebrand factor and alpha-thrombin. 1996 Apr 16 4
40 8883288 Inhibitory effect of prostacyclin and nitroprusside on type IIB von Willebrand factor-promoted platelet activation. 1996 Sep 4
41 7537105 Protein tyrosine phosphorylation in human platelets induced by interaction between glycoprotein Ib and von Willebrand factor. 1995 Apr 13 3
42 7721887 Identification of three tyrosine residues of glycoprotein Ib alpha with distinct roles in von Willebrand factor and alpha-thrombin binding. 1995 Apr 21 2
43 8585015 Protein tyrosine phosphorylation in human platelets during shear stress-induced platelet aggregation (SIPA) is regulated by glycoprotein (GP) Ib/IX as well as GP IIb/IIIa and requires intact cytoskeleton and endogenous ADP. 1995 Aug 4
44 7523416 Adhesion receptor activation of phosphatidylinositol 3-kinase. von Willebrand factor stimulates the cytoskeletal association and activation of phosphatidylinositol 3-kinase and pp60c-src in human platelets. 1994 Oct 28 1
45 7524475 Shear-stress-induced von Willebrand factor binding to platelets causes the activation of tyrosine kinase(s). 1994 Sep 15 2
46 8161783 Shear stress enhances the proteolysis of von Willebrand factor in normal plasma. 1994 Apr 15 1
47 1898735 Sulfation of Tyr1680 of human blood coagulation factor VIII is essential for the interaction of factor VIII with von Willebrand factor. 1991 Jan 15 2