Title : Platelet activation by von Willebrand factor requires coordinated signaling through thromboxane A2 and Fc gamma IIA receptor.

Pub. Date : 2001 Jul 13

PMID : 11344169






2 Functional Relationships(s)
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1 Here we show that binding of vWF to platelets induces the tyrosine phosphorylation of Fc gamma RIIA by a Src kinase. Tyrosine von Willebrand factor Homo sapiens
2 Similarly, vWF-induced tyrosine phosphorylation of Fc gamma RIIA, as well as of Syk and PLC gamma 2, occurs normally in aspirinized platelets. Tyrosine von Willebrand factor Homo sapiens