Alanine

von Willebrand factor ; Homo sapiens







17 Article(s)
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1 31675465 Unique surface-exposed hydrophobic residues in the C1 domain of factor VIII contribute to cofactor function and von Willebrand factor binding. 2020 Feb 2
2 24283831 The von Willebrand factor predicted unpaired cysteines are essential for secretion. 2014 Feb 1
3 22754302 Role of 14-3-3ζ in platelet glycoprotein Ibα-von Willebrand factor interaction-induced signaling. 2012 1
4 18923835 Impact of 789Ala/Ala genotype on quantitative type of von Willebrand disease. 2009 May 3
5 19875727 Identification of a novel 14-3-3zeta binding site within the cytoplasmic domain of platelet glycoprotein Ibalpha that plays a key role in regulating the von Willebrand factor binding function of glycoprotein Ib-IX. 2009 Dec 4 2
6 18369690 Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged-to-alanine-scanning mutagenesis. 2008 May 1
7 15606553 Impact of O-linked glycosylation of the VWF-A1-domain flanking regions on platelet interaction. 2005 Jan 1
8 12969981 Deletion of alanine 2201 in the FVIII C2 domain results in mild hemophilia A by impairing FVIII binding to VWF and phospholipids and destroys a major FVIII antigenic determinant involved in inhibitor development. 2004 Jan 1 1
9 14757772 Identification of the amino acid residues of the platelet glycoprotein Ib (GPIb) essential for the von Willebrand factor binding by clustered charged-to-alanine scanning mutagenesis. 2004 Apr 16 1
10 12069583 Binding site on human von Willebrand factor of bitiscetin, a snake venom-derived platelet aggregation inducer. 2002 Jun 25 1
11 10648402 Requirement of leucine-rich repeats of glycoprotein (GP) Ibalpha for shear-dependent and static binding of von Willebrand factor to the platelet membrane GP Ib-IX-V complex. 2000 Feb 1 1
12 11876992 [Construction and transient expression of an Ala 737-->Glu mutant of vWF]. 2000 May 1
13 9657753 Binding of factor VIII to von willebrand factor is enabled by cleavage of the von Willebrand factor propeptide and enhanced by formation of disulfide-linked multimers. 1998 Jul 15 1
14 9865467 Ser752 mutation to Pro or Ala in the beta3 integrin subunit differentially affects the kinetics of cell spreading to von Willebrand factor and fibrinogen. 1998 1
15 7539426 Identification of amino acid residues essential for von Willebrand factor binding to platelet glycoprotein Ib. Charged-to-alanine scanning mutagenesis of the A1 domain of human von Willebrand factor. 1995 Jun 2 3
16 8120035 Disulfide bonds required to assemble functional von Willebrand factor multimers. 1994 Mar 4 1
17 1737795 Selective inactivation of the Arg-Gly-Asp-Ser (RGDS) binding site in von Willebrand factor by site-directed mutagenesis. 1992 Feb 15 1