| 1 |
34923394 | Dynamic interaction network involving the conserved intrinsically disordered regions in human eIF5. | 2022 Feb |
1 |
| 2 |
35171475 | Quantifying the Binding of Fluorescently Labeled Guanine Nucleotides and Initiator tRNA to Eukaryotic Translation Initiation Factor 2. | 2022 |
6 |
| 3 |
34877508 | GTP binding to translation factor eIF2B stimulates its guanine nucleotide exchange activity. | 2021 Dec 17 |
1 |
| 4 |
30576497 | A network of eIF2β interactions with eIF1 and Met-tRNAi promotes accurate start codon selection by the translation preinitiation complex. | 2019 Mar 18 |
1 |
| 5 |
31048492 | Structural basis for eIF2B inhibition in integrated stress response. | 2019 May 3 |
1 |
| 6 |
29425030 | eIF2B Mechanisms of Action and Regulation: A Thermodynamic View. | 2018 Mar 6 |
1 |
| 7 |
29666249 | eIF1 Loop 2 interactions with Met-tRNAi control the accuracy of start codon selection by the scanning preinitiation complex. | 2018 May 1 |
2 |
| 8 |
30211544 | Human eIF5 and eIF1A Compete for Binding to eIF5B. | 2018 Oct 9 |
2 |
| 9 |
30281470 | Modeling and Dynamic Behavior of eIF2 Dependent Regulatory System With Disturbances. | 2018 Oct |
1 |
| 10 |
29036434 | Novel mechanisms of eIF2B action and regulation by eIF2α phosphorylation. | 2017 Nov 16 |
4 |
| 11 |
26705305 | Moco biosynthesis and the ATAC acetyltransferase engage translation initiation by inhibiting latent PKR activity. | 2016 Feb |
2 |
| 12 |
26717981 | Sliding of a 43S ribosomal complex from the recognized AUG codon triggered by a delay in eIF2-bound GTP hydrolysis. | 2016 Feb 29 |
2 |
| 13 |
25762631 | Depletion of eIF2·GTP·Met-tRNAi translation initiation complex up-regulates BRCA1 expression in vitro and in vivo. | 2015 Mar 30 |
1 |
| 14 |
24335188 | Enhanced eIF1 binding to the 40S ribosome impedes conformational rearrangements of the preinitiation complex and elevates initiation accuracy. | 2014 Feb |
4 |
| 15 |
24499181 | The scanning mechanism of eukaryotic translation initiation. | 2014 |
2 |
| 16 |
25486352 | A new function and complexity for protein translation initiation factor eIF2B. | 2014 |
1 |
| 17 |
24095748 | Synthesis and SAR study of novel 3,3-diphenyl-1,3-dihydroindol-2-one derivatives as potent eIF2·GTP·Met-tRNAiMet ternary complex inhibitors. | 2013 Nov |
2 |
| 18 |
22683627 | The binding mechanism of eIF2β with its partner proteins, eIF5 and eIF2Bε. | 2012 Jul 6 |
2 |
| 19 |
19808042 | A mechanistic model of nutritional control of protein synthesis in animal tissues. | 2010 Jan 21 |
1 |
| 20 |
20048003 | Regulatory elements in eIF1A control the fidelity of start codon selection by modulating tRNA(i)(Met) binding to the ribosome. | 2010 Jan 1 |
1 |
| 21 |
20485439 | eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation. | 2010 May 20 |
1 |
| 22 |
21204011 | Crystal structure of the C-terminal domain of the ɛ subunit of human translation initiation factor eIF2B. | 2010 Jun |
3 |
| 23 |
19835415 | How does a scanning ribosomal particle move along the 5'-untranslated region of eukaryotic mRNA? Brownian Ratchet model. | 2009 Nov 17 |
1 |
| 24 |
18160716 | A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of eukaryotic initiation factor 2B. | 2008 Mar |
1 |
| 25 |
18631136 | Clues to the mechanism of action of eIF2B, the guanine-nucleotide-exchange factor for translation initiation. | 2008 Aug |
2 |
| 26 |
18639529 | Intersubunit and interprotein interactions of alpha- and beta-subunits of human eIF2: Effect of phosphorylation. | 2008 Sep 19 |
1 |
| 27 |
17923239 | Identifying small molecule inhibitors of eukaryotic translation initiation. | 2007 |
1 |
| 28 |
16362046 | The fidelity of translation initiation: reciprocal activities of eIF1, IF3 and YciH. | 2006 Jan 11 |
1 |
| 29 |
16461768 | Interaction between eukaryotic initiation factors 1A and 5B is required for efficient ribosomal subunit joining. | 2006 Mar 31 |
1 |
| 30 |
16582624 | Localization of the translational guanine nucleotide exchange factor eIF2B: a common theme for GEFs? | 2006 Apr |
2 |
| 31 |
16584190 | Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors. | 2006 Apr 11 |
2 |
| 32 |
16924118 | Structure of archaeal translational initiation factor 2 betagamma-GDP reveals significant conformational change of the beta-subunit and switch 1 region. | 2006 Aug 29 |
1 |
| 33 |
16928960 | Initiation of protein synthesis by hepatitis C virus is refractory to reduced eIF2.GTP.Met-tRNA(i)(Met) ternary complex availability. | 2006 Nov |
2 |
| 34 |
16973618 | Distinct induction patterns and functions of two closely related interferon-inducible human genes, ISG54 and ISG56. | 2006 Nov 10 |
1 |
| 35 |
16990799 | An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation. | 2006 Oct 4 |
2 |
| 36 |
16157703 | Dynamic cycling of eIF2 through a large eIF2B-containing cytoplasmic body: implications for translation control. | 2005 Sep 12 |
2 |
| 37 |
16193068 | The eIF1A C-terminal domain promotes initiation complex assembly, scanning and AUG selection in vivo. | 2005 Oct 19 |
2 |
| 38 |
16246087 | Alternative mechanisms of initiating translation of mammalian mRNAs. | 2005 Dec |
1 |
| 39 |
14681227 | Structure of the catalytic fragment of translation initiation factor 2B and identification of a critically important catalytic residue. | 2004 Mar 12 |
1 |
| 40 |
15145951 | Efficient incorporation of eukaryotic initiation factor 1 into the multifactor complex is critical for formation of functional ribosomal preinitiation complexes in vivo. | 2004 Jul 23 |
1 |
| 41 |
15277680 | Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells. | 2004 Aug 3 |
2 |
| 42 |
15601822 | Release of initiation factors from 48S complexes during ribosomal subunit joining and the link between establishment of codon-anticodon base-pairing and hydrolysis of eIF2-bound GTP. | 2004 Dec 15 |
5 |
| 43 |
12493757 | Mammalian translation initiation factor eIF1 functions with eIF1A and eIF3 in the formation of a stable 40 S preinitiation complex. | 2003 Feb 21 |
2 |
| 44 |
12514125 | Domains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivo. | 2003 Jan 15 |
1 |
| 45 |
12885778 | Viral stress-inducible protein p56 inhibits translation by blocking the interaction of eIF3 with the ternary complex eIF2.GTP.Met-tRNAi. | 2003 Oct 10 |
2 |
| 46 |
11859078 | Crystal structure of the N-terminal segment of human eukaryotic translation initiation factor 2alpha. | 2002 May 10 |
1 |
| 47 |
11861906 | Phosphorylation of mammalian translation initiation factor 5 (eIF5) in vitro and in vivo. | 2002 Mar 1 |
2 |
| 48 |
11166181 | Eukaryotic translation initiation factor 5 (eIF5) acts as a classical GTPase-activator protein. | 2001 Jan 9 |
1 |
| 49 |
11323413 | Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein. | 2001 Jul 6 |
1 |
| 50 |
11726195 | Catalysis of guanine nucleotide exchange on eIF2 by eIF2B: can it be both a substituted enzyme and a sequential mechanism? | 2001 Dec 7 |
1 |