Inositol 1,4,5-Trisphosphate

phospholipase C gamma 1 ; Homo sapiens







26 Article(s)
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1 33792909 Ca2+ signalling is critical for autoantibody-induced blistering of human epidermis in pemphigus. 2021 Sep 1
2 31953353 OSBP-Related Protein 5L Maintains Intracellular IP3/Ca2+ Signaling and Proliferation in T Cells by Facilitating PIP2 Hydrolysis. 2020 Mar 1 2
3 27759161 Phospholipase Cγ1 is required for pre-TCR signal transduction and pre-T cell development. 2017 Jan 1
4 26588873 Roles of phosphoinositide-specific phospholipase Cγ1 in brain development. 2016 Jan 1
5 25916191 Scaffold Protein SLP-76 Primes PLCγ1 for Activation by ITK-Mediated Phosphorylation. 2015 Aug 28 1
6 26633375 DAG/PKCδ and IP3/Ca²⁺/CaMK IIβ Operate in Parallel to Each Other in PLCγ1-Driven Cell Proliferation and Migration of Human Gastric Adenocarcinoma Cells, through Akt/mTOR/S6 Pathway. 2015 Dec 1 3
7 24866019 A PLCγ1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries. 2014 May 27 2
8 25252913 A recurrent activating PLCG1 mutation in cardiac angiosarcomas increases apoptosis resistance and invasiveness of endothelial cells. 2014 Nov 1 1
9 19179337 Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1. 2009 Mar 27 3
10 17531443 Phospholipase C-gamma1 potentiates integrin-dependent cell spreading and migration through Pyk2/paxillin activation. 2007 Aug 2
11 12682243 Regulation of T cell activation and tolerance by phospholipase C gamma-1-dependent integrin avidity modulation. 2003 Apr 15 1
12 12771140 Src kinase mediates the regulation of phospholipase C-gamma activity by glycosphingolipids. 2003 Aug 15 1
13 11823862 Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE. 2002 Jan 31 2
14 11956293 HIV-1 Nef interacts with inositol trisphosphate receptor to activate calcium signaling in T cells. 2002 Apr 15 2
15 10700379 Effect of limited proteolysis on phospholipase C-gamma1 kinetics. 2000 Mar 15 1
16 11048639 The mechanism of phospholipase C-gamma1 regulation. 2000 Sep 30 1
17 10100621 Role of tyrosine phosphorylation of phospholipase C gamma1 in the signaling pathway of HMG-CoA reductase inhibitor-induced cell death of L6 myoblasts. 1999 Mar 5 1
18 10373546 Physiological requirement for both SH2 domains for phospholipase C-gamma1 function and interaction with platelet-derived growth factor receptors. 1999 Jul 1
19 10419537 Overactivation of phospholipase C-gamma1 renders platelet-derived growth factor beta-receptor-expressing cells independent of the phosphatidylinositol 3-kinase pathway for chemotaxis. 1999 Jul 30 2
20 10672930 The SH2-SH2-SH3 domain of phospholipase C-gamma1 directly binds to translational elongation factor-1alpha. 1999 Dec 31 2
21 9226298 Calcium-dependent and calcium-independent activation of the endothelial NO synthase. 1997 May-Jun 1
22 9293962 Tyrosine phosphorylation and bradykinin-induced signaling in endothelial cells. 1997 Aug 4 1
23 7487955 Early signalling mechanism in colonic epithelial cell response to gastrin. 1995 Nov 1 2
24 7822789 Human p59fyn(T) regulates OKT3-induced calcium influx by a mechanism distinct from PIP2 hydrolysis in Jurkat T cells. 1995 Feb 1 2
25 8034732 Erythropoietin induces tyrosine phosphorylation and activation of phospholipase C-gamma 1 in a human erythropoietin-dependent cell line. 1994 Jul 29 3
26 8327490 7,12-Dimethylbenz[a]anthracene activates protein-tyrosine kinases Fyn and Lck in the HPB-ALL human T-cell line and increases tyrosine phosphorylation of phospholipase C-gamma 1, formation of inositol 1,4,5-trisphosphate, and mobilization of intracellular calcium. 1993 Jul 1 1