Guanosine Diphosphate

GNAS complex locus ; Homo sapiens







14 Article(s)
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1 16760361 Mutagenesis within helix 6 of the human beta1-adrenergic receptor identifies Lysine324 as a residue involved in imparting the high-affinity binding state of agonists. 2006 Sep 2
2 15368366 Mutation of the highly conserved Arg165 and Glu168 residues of human Gsalpha disrupts the alphaD-alphaE loop and enhances basal GDP/GTP exchange rate. 2004 Oct 1 1
3 11318657 Inhibition of GDP/GTP exchange on G alpha subunits by proteins containing G-protein regulatory motifs. 2001 May 1 1
4 10644728 Rhodopsin recognition by mutant G(s)alpha containing C-terminal residues of transducin. 2000 Jan 28 1
5 10649434 Mutagenesis in the switch IV of the helical domain of the human Gsalpha reduces its GDP/GTP exchange rate. 2000 Jan 2
6 9988742 Mutagenesis of the conserved residue Glu259 of Gsalpha demonstrates the importance of interactions between switches 2 and 3 for activation. 1999 Feb 19 2
7 10714366 Gs alpha mutations in hyperfunctioning thyroid adenomas. 1999 Nov-Dec 1
8 9727013 A novel mutation in the switch 3 region of Gsalpha in a patient with Albright hereditary osteodystrophy impairs GDP binding and receptor activation. 1998 Sep 11 5
9 9328353 A novel mutation adjacent to the switch III domain of G(S alpha) in a patient with pseudohypoparathyroidism. 1997 Oct 1
10 8621516 Chloride effects on Gs subunit dissociation. Fluoroaluminate binding to Gs does not cause subunit dissociation in the absence of chloride ion. 1996 Apr 12 1
11 8736705 GTP binding to Gs does not promote subunit dissociation. 1996 Mar 2
12 8865363 GTP synthases. Proton pumping and phosphorylation in ligand-receptor-G alpha-protein complexes. 1996 1
13 8063706 Mutation of valine residue unique to alpha subunit of Gs abolishes activation. 1994 Aug 19 1
14 8072545 Rapid GDP release from Gs alpha in patients with gain and loss of endocrine function. 1994 Sep 8 1